Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.53 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.53 |
| ▸ | GPR183 | P32249 | 1/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.49 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.49 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.49 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.49 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.49 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.49 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.49 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.48 |
| ▸ | HPGDS | O60760 | 3/20 | 0.48 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | ATR | Q13535 | 1/20 | 0.47 |
| ▸ | BMPR1B | O00238 | 2/20 | 0.46 |
| ▸ | BMPR1A | P36894 | 2/20 | 0.46 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL960202 | 0.87 | RAB9A (0.50) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL26944377 | 0.85 | HDAC6 (0.53) | AURKAAURKBEGLN1PRKAB2PRKAG1 | |
| SCHEMBL2159144 | 0.84 | GRM5 (0.53) | — | |
| SCHEMBL3544572 | 0.84 | SSTR5 (0.56) | AURKAAURKBEGLN1PRKAB2PRKAG1 | |
| SCHEMBL2159094 | 0.83 | GRM5 (0.57) | — | |
| SCHEMBL20551505 | 0.81 | NPSR1 (0.54) | AURKAAURKBSLC6A5HDAC4HDAC6 | |
| SCHEMBL2069780 | 0.80 | HPGDS (0.69) | EGLN1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL12776620 | 0.78 | HPGDS (0.53) | EGLN1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL2073316 | 0.78 | HPGDS (0.58) | EGLN1HPGDSSLC6A5HDAC4HDAC6 | |
| SCHEMBL4636340 | 0.77 | GABRA5 (0.55) | AURKBPRKAB2PRKAG1PRKAA2PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551593-A | Compounds and methods for modulating splicing | 雷密克斯医疗公司 | 2022-12-30 | — | — | CN | disclosed |