Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ARG1 | P05089 | 11/20 | 0.46 |
| ▸ | ARG2 | P78540 | 11/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL895073 | 1.00 | LMNA (0.49) | LMNAARG1ARG2SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL894306 | 0.99 | LMNA (0.48) | LMNAARG1ARG2SMN1; SMN2MAPT | |
| SCHEMBL19055955 | 0.90 | ARG1 (0.47) | LMNAARG1ARG2SMN1; SMN2MAPT | |
| SCHEMBL20683433 | 0.84 | LMNA (0.52) | LMNASMN1; SMN2MAPTNPY1RNPY2R | |
| SCHEMBL18079736 | 0.77 | ARG1 (0.46) | ARG1ARG2 | |
| SCHEMBL10006331 | 0.76 | ARG1 (0.54) | ARG1ARG2MAPTALDH1A1 | |
| SCHEMBL29657538 | 0.76 | ARG1 (0.54) | ARG1ARG2MAPTALDH1A1 | |
| SCHEMBL894933 | 0.74 | ARG1 (0.57) | ARG1ARG2 | |
| SCHEMBL30169912 | 0.74 | ARG1 (0.47) | ARG1ARG2 | |
| SCHEMBL10006413 | 0.74 | ARG1 (0.47) | ARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283332-A1 | USES OF ARGINASE INHIBITORS FOR MANAGING KIDNEY DISEASE AND CARDIOVASCULAR CONDITIONS | EMORY UNIVERSITY (US) | 2023-01-12 | — | — | WO | disclosed |