Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 11/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30169871 | 0.84 | LMNA (0.49) | LMNASMN1; SMN2IDO1MAPTALDH1A1 | |
| SCHEMBL895073 | 0.84 | LMNA (0.49) | LMNASMN1; SMN2IDO1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL894306 | 0.83 | LMNA (0.48) | LMNASMN1; SMN2IDO1MAPTALDH1A1 | |
| SCHEMBL19055955 | 0.73 | ARG1 (0.47) | LMNASMN1; SMN2MAPTALDH1A1KMT2A | |
| SCHEMBL10786460 | 0.70 | LMNA (0.82) | LMNASMN1; SMN2IDO1MAPTALDH1A1 | |
| SCHEMBL13737508 | 0.70 | LMNA (0.63) | LMNASMN1; SMN2IDO1MAPTALDH1A1 | |
| SCHEMBL10662740 | 0.70 | LMNA (0.67) | LMNASMN1; SMN2IDO1MAPTALDH1A1 | |
| SCHEMBL13735975 | 0.68 | LMNA (0.69) | LMNASMN1; SMN2IDO1MAPTALDH1A1 | |
| SCHEMBL4555003 | 0.66 | IDO1 (0.78) | LMNASMN1; SMN2IDO1MAPTALDH1A1 | |
| SCHEMBL20683491 | 0.66 | ARG1 (0.48) | ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560978-B1 | INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS | MARS INC (US) | 2019-01-30 | — | — | EP | disclosed |