SCHEMBL301699

SCHEMBL301699

c1ccc(CN2CCN(Cc3ccccc3)C2)cc1

nearest known ligand 0.81

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 7/20 0.81
MC4R P32245 1/20 0.65
DRD4 P21917 2/20 0.63
LMNA P02545 1/20 0.63
POLB P06746 1/20 0.63
CCR3 P51677 1/20 0.57
KMT2A Q03164 1/20 0.57
ACHE P22303 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11053834 0.91 SIGMAR1 (0.67) SIGMAR1MC4RDRD4LMNAPOLB
SCHEMBL1415730 0.90 SIGMAR1 (1.00) SIGMAR1MC4RDRD4LMNAPOLB
SCHEMBL1041303 0.90 SIGMAR1 (1.00) SIGMAR1MC4RDRD4LMNAPOLB
SCHEMBL242970 0.90 SIGMAR1 (1.00) SIGMAR1MC4RDRD4LMNAPOLB
SCHEMBL1639911 0.90 SIGMAR1 (0.71) SIGMAR1MC4RDRD4LMNAPOLB
SCHEMBL2489199 0.90 SIGMAR1 (1.00) SIGMAR1MC4RDRD4LMNAPOLB
SCHEMBL576868 0.90 SIGMAR1 (1.00) SIGMAR1MC4RDRD4LMNAPOLB
SCHEMBL8188324 0.90 SIGMAR1 (1.00) SIGMAR1MC4RDRD4LMNAPOLB
SCHEMBL15689951 0.88 CCR3 (0.66) SIGMAR1MC4RDRD4LMNAPOLB
SCHEMBL4448723 0.87 SIGMAR1 (0.68) SIGMAR1MC4RDRD4LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115128207-B Standard method for detecting free acid content in polybasic organic carboxylic acid product 安徽圣达生物药业有限公司 2024-12-13 CN claimed
CN-115466217-B Method for recycling cyclic acid 安徽泰格维生素实业有限公司 2024-01-30 CN claimed
CN-113801125-B Preparation method of cyclic anhydride 安徽泰格维生素实业有限公司 2023-11-03 CN claimed
CN-117362303-A Preparation method of biotin intermediate cyclic anhydride 黑龙江联顺生物科技有限公司 2024-01-09 CN disclosed
CN-113801125-B Preparation method of cyclic anhydride 安徽泰格维生素实业有限公司 2023-11-03 CN disclosed
CN-115466217-A Method for recovering cyclic acid 安徽泰格维生素实业有限公司 2022-12-13 CN disclosed
CN-114634515-A Stereoselective synthesis method of (3aS,6aR) -lactone 复旦大学 2022-06-17 CN disclosed
CN-114560865-A Continuous flow synthesis method of (3aS,6aR) -lactone 复旦大学 2022-05-31 CN disclosed
US-20210079593-A1 Dissolution of Cellulose in Ionic Liquids TEXAS TECH UNIVERSITY SYSTEM 2021-03-18 US disclosed
US-10588222-B2 Coating metal foil with n-heterocyclic carbene compounds containing organic functionalities for improving metal-to-resin adhesion INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2020-03-10 US disclosed
US-20200053886-A1 COATING METAL FOIL WITH N-HETEROCYCLIC CARBENE COMPOUNDS CONTAINING ORGANIC FUNCTIONALITIES FOR IMPROVING METAL-TO-RESIN ADHESION INTERNATIONAL BUSINESS MACHINES CORPORATION 2020-02-13 US disclosed
EP-0585869-A1 Solid titanium catalyst component for olefin polymerization, process for preparing the same, catalyst for olefin polymerization and process for olefin polymerization MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-03-09 EP disclosed
EP-0536503-A2 Olefin polymer composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-04-14 EP disclosed
EP-0534119-A2 Prepolymerized olefin polymerization catalyst and olefin polymerization process MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-03-31 EP disclosed
CN-1057656-A Solid titanium catalyst component for olefin polymerization, olefin polymerization catalyst, prepolymerized polyolefin-containing catalyst, and process for olefin polymerization MITSUI PETROCHEMICAL IND (JP) 1992-01-08 CN disclosed
EP-0452156-A2 Solid titanium catalyst component for olefin polymerization, olefin polymerization catalyst, prepolymerized polyolefin-containing catalyst and method of olefin polymerization MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-10-16 EP disclosed
EP-0086645-B1 CATALYST COMPOSITION AND PROCESS FOR POLYMERIZING OLEFINS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1986-09-24 EP disclosed
EP-0056156-B1 METHOD OF IMPROVING ADHESION BETWEEN RUBBER AND METALS BAYER AG (DE) 1984-11-21 EP disclosed
EP-0086645-A2 Catalyst composition and process for polymerizing olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1983-08-24 EP disclosed
EP-0056156-A1 Method of improving adhesion between rubber and metals BAYER AG (DE) 1982-07-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210079593-A1 Dissolution of Cellulose in Ionic Liquids CEL, MGAM, SI SIGMAR1 2187/4885MC4R 2492/4885DRD4 1545/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.