Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.30 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3001113 | 0.94 | ACHE (0.31) | ACHEALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL3009651 | 0.92 | NOD2 (0.34) | ALDH1A1POLBNOD2NOD1 | |
| Hydrochloric Acid SCHEMBL3014095 | 0.91 | ACHE (0.33) | ACHEALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL3015747 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL3011630 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL2999706 | 0.85 | NPC1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL3005655 | 0.85 | ACHE (0.32) | ACHEALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL2999415 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL3012431 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL3009974 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190941-A1 | TRANSITION METAL COMPOUND, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER | MITSUI CHEMICALS, INC. | 2010-07-29 | — | — | US | disclosed |
| US-20090043057-A1 | Transition Metal Compound, Catalyst for Olefin Polymerization, and Process for Producing Olefin Polymer | MITSUI CHEMICALS , INC. | 2009-02-12 | — | — | US | disclosed |
| EP-1900744-A1 | TRANSITION METAL COMPOUND, OLEFIN POLYMERIZATION CATALYST, AND PROCESS FOR PRODUCING OLEFIN POLYMER | Mitsui Chemicals, Inc. (JP) | 2008-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090043057-A1 | Transition Metal Compound, Catalyst for Olefin Polymerization, and Process for Producing Olefin Polymer | OR10J3, PYM1, CCNE2 | ACHE 4168/4885ALDH1A1 4123/4885POLB 809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.