SCHEMBL30171202

SCHEMBL30171202

O=C1N=C2C=CCC=C2c2ccccc21

nearest known ligand 0.30

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.30
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30
CDC25B P30305 1/20 0.30
AKT1 P31749 1/20 0.30
SNCA P37840 1/20 0.30
MAP2K1 Q02750 1/20 0.30
PIN1 Q13526 1/20 0.30
EHMT2 Q96KQ7 1/20 0.30
NSD1 Q96L73 1/20 0.30
EHMT1 Q9H9B1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1357123 0.79 IDO1 (0.31) IDO1
SCHEMBL29913884 0.79 IDO1 (0.31) IDO1
SCHEMBL10977948 0.77 MEN1 (0.36) MAOAMAOBCDC25B
SCHEMBL29935584 0.73 KDM4E (0.32)
SCHEMBL607872 0.71 TDP2 (0.37) CDC25B
SCHEMBL8323390 0.68 CDC25B (0.33) IDO1MAOAMAOBCDC25BAKT1
SCHEMBL9389374 0.68
SCHEMBL422015 0.64 S100A4 (0.34) CDC25B
SCHEMBL30229889 0.64 S100A4 (0.34) CDC25B
SCHEMBL1646179 0.62 MEN1 (0.40) IDO1MAOAMAOBCDC25BAKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115677714-B Intermediate in preparation of (+) -water podocarpine and application thereof 昆明医科大学 2024-06-11 CN disclosed
CN-115894507-B Synthesis method and application of (+) -water podocarpine 昆明医科大学 2024-06-07 CN disclosed
CN-115894507-A Method for synthesizing (+) -canna oensis alkali and application thereof 昆明医科大学 2023-04-04 CN disclosed
CN-115677714-A Intermediate in preparation of (+) -coprinus comatus alkali and application thereof 昆明医科大学 2023-02-03 CN disclosed