SCHEMBL30229889

SCHEMBL30229889

O=C1N=C2SCC=C2c2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 1/20 0.34
ACHE P22303 1/20 0.33
MEN1 O00255 1/20 0.30
CDC25B P30305 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL422015 1.00 S100A4 (0.34) S100A4ACHEMEN1CDC25BKMT2A
SCHEMBL30171202 0.64 IDO1 (0.30) CDC25B
SCHEMBL8323390 0.63 CDC25B (0.33) S100A4MEN1CDC25BKMT2A
SCHEMBL8346897 0.61 MEN1 (0.36) S100A4MEN1CDC25BKMT2A
SCHEMBL527160 0.60 ABCG2 (0.46) S100A4ACHEMEN1CDC25BKMT2A
SCHEMBL30624821 0.60 MEN1 (0.31) S100A4MEN1CDC25BKMT2A
SCHEMBL2359460 0.60 IDO1 (0.44) S100A4MEN1CDC25BKMT2A
SCHEMBL879050 0.60 CDC25B (0.39) S100A4MEN1CDC25BKMT2A
SCHEMBL2026326 0.60 MEN1 (0.39) S100A4MEN1CDC25BKMT2A
SCHEMBL31131321 0.60 LMNA (0.45) S100A4MEN1CDC25BKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4554683-A2 METHOD FOR TREATING BREAST CANCERS AND PARP RESISTANT BREAST CANCERS Lantern Pharma Inc. (US) 2025-05-21 EP disclosed
EP-4376822-A1 TREATING CANCERS WITH COMBINATIONS OF PARP INHIBITOR AND ACYLFULVENES Lantern Pharma Inc. (US) 2024-06-05 EP disclosed
WO-2024016014-A2 METHOD FOR TREATING BREAST CANCERS AND PARP RESISTANT BREAST CANCERS LANTERN PHARMA INC. (US) 2024-01-18 WO disclosed
US-20230065522-A1 METHODS OF CANCER DETECTION USING PARPI-FL MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2023-03-02 US disclosed
WO-2023010119-A1 TREATING CANCERS WITH COMBINATIONS OF PARP INHIBITOR AND ACYLFULVENES LANTERN PHARMA INC. (US) 2023-02-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230065522-A1 METHODS OF CANCER DETECTION USING PARPI-FL PARP2, PARP1, PARP3 S100A4 785/4885ACHE 4647/4885MEN1 3121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.