SCHEMBL30171452

SCHEMBL30171452

c1cnc2c(c1)ccc1c3ccccc3sc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.48
MAPT P10636 4/20 0.48
KDM4E B2RXH2 3/20 0.48
CCR1 P32246 3/20 0.48
CCR8 P51685 3/20 0.48
CCR5 P51681 2/20 0.48
CYP3A4 P08684 2/20 0.48
MMP2 P08253 2/20 0.48
TSHR P16473 2/20 0.48
GMNN O75496 1/20 0.48
TP53 P04637 1/20 0.48
HSP90AA1 P07900 1/20 0.48
CYP2D6 P10635 1/20 0.48
MMP9 P14780 1/20 0.48
ALOX15 P16050 1/20 0.48
NFKB1 P19838 1/20 0.48
MMP8 P22894 1/20 0.48
THPO P40225 1/20 0.48
MTOR P42345 1/20 0.48
HTT P42858 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18647368 0.89 MAPT (0.45) LMNAMAPTKDM4ECCR1CCR8
SCHEMBL25671886 0.81 LIMK1 (0.40) LMNAMAPTKDM4ECCR1CCR8
SCHEMBL25461964 0.80 ALDH1A1 (0.42) LMNAMAPTKDM4ECCR1CCR8
SCHEMBL25672224 0.80 NR4A2 (0.45) LMNAMAPTKDM4ECCR1CCR8
SCHEMBL21030541 0.80 CYP3A4 (0.44) LMNAMAPTKDM4ECCR1CCR8
SCHEMBL21622648 0.80 LMNA (0.44) LMNAMAPTKDM4ECCR1CCR8
SCHEMBL21622848 0.80 LMNA (0.44) LMNAMAPTKDM4ECCR1CCR8
SCHEMBL21622847 0.80 ALOX5 (0.49) LMNAMAPTKDM4ECCR1CCR8
SCHEMBL25462076 0.79 CCR1 (0.41) LMNAMAPTKDM4ECCR1CCR8
SCHEMBL21622636 0.79 LMNA (0.43) LMNAMAPTKDM4ECCR1CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250074925-A1 RARE EARTH COMPLEX SAGAMI CHEMICAL RESEARCH INSTITUTE (JP) 2025-03-06 US disclosed
EP-4365180-A1 RARE EARTH COMPLEX Tosoh Corporation (JP) 2024-05-08 EP disclosed
WO-2023282236-A1 RARE EARTH COMPLEX 東ソー株式会社 2023-01-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250074925-A1 RARE EARTH COMPLEX L1CAM, CHRM1, NPM1 LMNA 674/4885MAPT 3174/4885KDM4E 4590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.