Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.86 |
| ▸ | GAA | P10253 | 2/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.66 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28497414 | 1.00 | LMNA (0.86) | LMNAGAACYP1A2CYP2C9CYP3A4 | |
| SCHEMBL3253283 | 0.85 | CYP3A4 (0.70) | LMNAGAACYP1A2CYP2C9CYP3A4 | |
| SCHEMBL16610098 | 0.85 | MAPT (0.84) | LMNAGAACYP1A2CYP2C9CYP3A4 | |
| SCHEMBL4067164 | 0.84 | CYP3A4 (1.00) | LMNACYP1A2CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL12335476 | 0.83 | NAMPT (0.73) | LMNACYP2C9SMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL29684017 | 0.83 | NAMPT (0.76) | LMNACYP1A2CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL6164416 | 0.83 | MAPT (0.71) | LMNAGAACYP1A2CYP2C9CYP3A4 | |
| SCHEMBL11613978 | 0.83 | ALDH1A1 (1.00) | LMNAGAACYP3A4MAPTALDH1A1 | |
| SCHEMBL2424556 | 0.83 | RECQL (0.72) | LMNACYP1A2CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL22575168 | 0.83 | GAA (0.64) | LMNAGAACYP1A2CYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112209847-B | Method for preparing amide compound under catalysis of ionic liquid in high-pressure environment | 烟台大学 | 2022-12-23 | — | — | CN | disclosed |