Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16610098 | 0.89 | MAPT (0.84) | CYP3A4CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL13271684 | 0.89 | CYP3A4 (0.80) | CYP3A4CYP1A2CYP2C9CYP2C19PAX8 | |
| SCHEMBL16353842 | 0.86 | CYP3A4 (0.76) | CYP3A4CYP1A2CYP2C9CYP2C19PAX8 | |
| SCHEMBL28687306 | 0.85 | CYP3A4 (0.73) | CYP3A4CYP1A2CYP2C9CYP2C19PAX8 | |
| SCHEMBL1566393 | 0.85 | CYP3A4 (0.73) | CYP3A4CYP1A2CYP2C9CYP2C19PAX8 | |
| SCHEMBL29354343 | 0.85 | CYP3A4 (0.73) | CYP3A4CYP1A2CYP2C9CYP2C19PAX8 | |
| SCHEMBL28497414 | 0.84 | LMNA (0.86) | CYP3A4CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL30172092 | 0.84 | LMNA (0.86) | CYP3A4CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL4075670 | 0.84 | CYP1A2 (0.73) | CYP3A4CYP1A2CYP2C9CYP2C19PAX8 | |
| SCHEMBL4071835 | 0.84 | CYP1A2 (0.73) | CYP3A4CYP1A2CYP2C9CYP2C19PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1190963-A | 2-amino-benzoxanones for the treatment of viral infections | SEARLE & CO (US) | 1998-08-19 | — | — | CN | claimed |
| EP-1415986-B1 | SPIRO ISOBENZOFURANES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | BANYU PHARMA CO LTD (JP) | 2009-04-08 | — | — | EP | disclosed |
| US-7205417-B2 | Spiro compounds | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-04-17 | — | — | US | disclosed |