Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TCF4 | P15884 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3360534 | 0.82 | CYP2C9 (0.41) | TDP1KDM4EMAPTL3MBTL1LMNA | |
| SCHEMBL3030889 | 0.77 | HIF1A (0.37) | TDP1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL27689436 | 0.76 | L3MBTL1 (0.33) | TDP1MAPTL3MBTL1LMNACYP2C9 | |
| SCHEMBL10125216 | 0.69 | POLB (0.45) | TDP1KDM4EMAPTL3MBTL1LMNA | |
| SCHEMBL28524426 | 0.67 | TSHR (0.49) | MAPTL3MBTL1POLBNPSR1MEN1 | |
| SCHEMBL17973534 | 0.67 | CYP2C9 (0.42) | TDP1KDM4EMAPTL3MBTL1LMNA | |
| SCHEMBL7709312 | 0.66 | CYP1A2 (0.46) | ALDH1A1KDM4EL3MBTL1LMNAPOLB | |
| SCHEMBL13302156 | 0.66 | CYP2C9 (0.49) | TDP1ALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL2184458 | 0.66 | CA1 (0.43) | TDP1ALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL30877445 | 0.66 | CYP2C9 (0.41) | ALDH1A1KDM4EMAPTL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100204187-A1 | Purine Derivatives | PALAU PHARMA, S.A. (ES) | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204187-A1 | Purine Derivatives | JAK3, JAK1, JAK2 | TDP1 579/4885ALDH1A1 1686/4885KDM4E 1790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.