Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 4/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 13/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
| ▸ | TEC | P42680 | 1/20 | 0.51 |
| ▸ | TXK | P42681 | 1/20 | 0.51 |
| ▸ | BMX | P51813 | 1/20 | 0.51 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.48 |
| ▸ | PRKDC | P78527 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28384616 | 0.92 | BTK (0.59) | BTKHDAC1MTORERBB2TEC | |
| SCHEMBL28469754 | 0.91 | MTOR (0.62) | BTKHDAC1MTORERBB2TEC | |
| SCHEMBL28380136 | 0.90 | BTK (0.55) | BTKHDAC1MTORERBB2TEC | |
| SCHEMBL30172728 | 0.90 | HDAC1 (0.51) | BTKHDAC1MTORPIK3CDPIK3CA | |
| SCHEMBL28380138 | 0.88 | LMNA (0.51) | BTKHDAC1MTORERBB2TEC | |
| SCHEMBL28412582 | 0.86 | BTK (0.69) | BTKHDAC1MTORBMXERBB4 | |
| SCHEMBL28383935 | 0.86 | BTK (0.61) | BTKHDAC1MTORERBB2TEC | |
| SCHEMBL28387491 | 0.85 | BTK (0.61) | BTKHDAC1MTORERBB2TEC | |
| SCHEMBL28382115 | 0.85 | BTK (0.53) | BTKHDAC1MTORERBB2TEC | |
| SCHEMBL28384506 | 0.84 | BTK (0.53) | BTKHDAC1MTORERBB2TEC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115572297-A | O-phenylenediamine derivative containing pyrazolopyrimidine and preparation method and application thereof | 山东大学 | 2023-01-06 | — | — | CN | claimed |
| CN-115572297-B | Pyrazolopyrimidine-containing o-phenylenediamine derivative, and preparation method and application thereof | 山东大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-115572297-A | O-phenylenediamine derivative containing pyrazolopyrimidine and preparation method and application thereof | 山东大学 | 2023-01-06 | — | — | CN | disclosed |