Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30173047 | 0.85 | AAK1 (0.35) | MAPK1 | |
| SCHEMBL24992624 | 0.85 | AAK1 (0.35) | MAPK1 | |
| SCHEMBL23089425 | 0.81 | PIK3CA (0.39) | — | |
| SCHEMBL23089222 | 0.80 | CNR2 (0.32) | MAPK1ABL1 | |
| SCHEMBL29239391 | 0.75 | — | — | |
| SCHEMBL23089133 | 0.75 | RAB9A (0.43) | MAPK1 | |
| SCHEMBL23089385 | 0.71 | MAPK1 (0.33) | MAPK1ABL1 | |
| SCHEMBL18992789 | 0.69 | ADORA3 (0.39) | — | |
| SCHEMBL23089587 | 0.69 | ACVR1 (0.38) | MAPK1 | |
| SCHEMBL30630161 | 0.67 | PIK3CA (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4380565-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2024-06-12 | — | — | EP | disclosed |
| WO-2023015199-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2023-02-09 | — | — | WO | disclosed |