Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 16/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700989 | 0.86 | MAPK1 (0.44) | HTR1DMAPK1 | |
| SCHEMBL16684568 | 0.76 | MAPK1 (0.42) | MAPK1 | |
| SCHEMBL529398 | 0.75 | TAAR1 (0.35) | — | |
| SCHEMBL30173034 | 0.72 | MAPK1 (0.42) | MAPK1DHFR | |
| SCHEMBL16678931 | 0.71 | MAPK1 (0.44) | MAPK1DHFR | |
| SCHEMBL21355171 | 0.70 | NOS3 (0.38) | MAPK1DHFR | |
| SCHEMBL20242152 | 0.68 | MAPK1 (0.39) | MAPK1DHFR | |
| SCHEMBL24738195 | 0.68 | KDM4E (0.34) | MAPK1 | |
| SCHEMBL21356631 | 0.67 | KDM4E (0.38) | MAPK1 | |
| SCHEMBL29792909 | 0.67 | KDM4E (0.38) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4380565-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2024-06-12 | — | — | EP | disclosed |
| CN-117915912-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2024-04-19 | — | — | CN | disclosed |
| WO-2023015199-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2023-02-09 | — | — | WO | disclosed |