SCHEMBL30700989

SCHEMBL30700989

CN(C)Cc1cc(C2CCOCC2)cnc1N

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 19/20 0.44
HTR1D P28221 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30173079 0.86 HTR1D (0.42) MAPK1HTR1D
SCHEMBL30865585 0.79 MAPK1 (0.31) MAPK1
SCHEMBL16684568 0.78 MAPK1 (0.42) MAPK1
SCHEMBL30172987 0.77 DRD2 (0.30)
SCHEMBL30173066 0.76 MAP4K1 (0.32) MAPK1
SCHEMBL16678931 0.76 MAPK1 (0.44) MAPK1
SCHEMBL30173034 0.74 MAPK1 (0.42) MAPK1
SCHEMBL22820726 0.74 MAP4K1 (0.49) MAPK1
SCHEMBL24992693 0.73 MBOAT4 (0.32) MAPK1
SCHEMBL19174963 0.72 SLC6A4 (0.39) MAPK1HTR1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117915912-A HPK1 antagonists and uses thereof 林伯士萨顿公司 2024-04-19 CN disclosed
CN-117377673-A HPK1 antagonists and uses thereof 林伯士萨顿公司 2024-01-09 CN disclosed
CN-117295737-A HPK1 antagonists and uses thereof 林伯士萨顿公司 2023-12-26 CN disclosed