Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 4/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | KMO | O15229 | 1/20 | 0.30 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15400514 | 1.00 | DGAT1 (0.35) | DGAT1HTR2AHTR2CMAPTPDE4D | |
| SCHEMBL29864422 | 0.89 | DGAT1 (0.35) | DGAT1HTR2AHTR2CMAPTF2RL1 | |
| SCHEMBL25345498 | 0.84 | DGAT1 (0.42) | DGAT1F2RL1 | |
| SCHEMBL25967058 | 0.84 | DGAT1 (0.35) | DGAT1HTR2AHTR2CMAPTF2RL1 | |
| SCHEMBL16437423 | 0.81 | KMO (0.50) | DGAT1HTR2AHTR2CKMO | |
| SCHEMBL30907146 | 0.79 | PDE10A (0.33) | DGAT1MAPT | |
| SCHEMBL25345157 | 0.79 | DGAT1 (0.45) | DGAT1 | |
| SCHEMBL24344127 | 0.78 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL13732447 | 0.77 | DGAT1 (0.39) | DGAT1MAPT | |
| SCHEMBL29777185 | 0.77 | DGAT1 (0.39) | DGAT1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115557947-B | Pyrazolo [4,3-c ] pyridine derivative and application thereof in medicine | 成都百裕制药股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115557947-A | Pyrazolo [4,3-c ] pyridine derivative and application thereof in medicine | 成都百裕制药股份有限公司 | 2023-01-03 | — | — | CN | disclosed |