Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30173195 | 0.79 | DGAT1 (0.35) | MAPTDGAT1 | |
| SCHEMBL29864422 | 0.79 | DGAT1 (0.35) | MAPTDGAT1 | |
| SCHEMBL15400514 | 0.79 | DGAT1 (0.35) | MAPTDGAT1 | |
| SCHEMBL1441946 | 0.79 | LMNA (0.37) | LMNA | |
| SCHEMBL30907555 | 0.78 | BRD4 (0.35) | MAPTDGAT1 | |
| SCHEMBL30226522 | 0.75 | CYP17A1 (0.35) | MAPTDGAT1LMNA | |
| SCHEMBL16793648 | 0.75 | CYP17A1 (0.35) | MAPTDGAT1LMNA | |
| SCHEMBL24328469 | 0.75 | HSP90AA1 (0.35) | MAPTDGAT1 | |
| SCHEMBL29661419 | 0.75 | HSP90AA1 (0.35) | MAPTDGAT1 | |
| SCHEMBL20262422 | 0.75 | DGAT1 (0.33) | MAPTDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097953-A1 | NAPHTHYRIDINE COMPOUNDS FOR INHIBITION OF RAF KINASES | ENLIVEN INC. (US) | 2024-05-10 | — | — | WO | disclosed |