Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 7/20 | 0.43 |
| ▸ | PPARD | Q03181 | 7/20 | 0.43 |
| ▸ | PPARA | Q07869 | 7/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28417400 | 0.83 | LMNA (0.48) | LMNATSHRNFKB1PMP22GPR84 | |
| SCHEMBL28084746 | 0.81 | TSHR (0.50) | LMNATSHRNFKB1PMP22GPR84 | |
| SCHEMBL9186664 | 0.81 | MEN1 (0.35) | TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL26861624 | 0.80 | LMNA (0.43) | LMNATSHRNFKB1PMP22GPR84 | |
| Adipic Acid SCHEMBL27660014 | 0.79 | LMNA (0.61) | LMNATSHRNFKB1PMP22GPR84 | |
| Adipic Acid SCHEMBL230983 | 0.77 | LMNA (0.58) | LMNATSHRNFKB1PMP22GPR84 | |
| Adipic Acid SCHEMBL536438 | 0.77 | LMNA (0.58) | LMNATSHRNFKB1PMP22GPR84 | |
| Adipic Acid SCHEMBL3475386 | 0.77 | LMNA (0.58) | LMNATSHRNFKB1PMP22GPR84 | |
| Adipic Acid SCHEMBL536963 | 0.77 | LMNA (0.58) | LMNATSHRNFKB1PMP22GPR84 | |
| Adipic Acid SCHEMBL536626 | 0.77 | LMNA (0.58) | LMNATSHRNFKB1PMP22GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115768807-A | Elastomeric materials prepared from energy curable liquid compositions | 阿科玛法国公司 | 2023-03-07 | — | — | CN | claimed |
| CN-115768807-A | Elastomeric materials prepared from energy curable liquid compositions | 阿科玛法国公司 | 2023-03-07 | — | — | CN | disclosed |