Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 7/20 | 0.50 |
| ▸ | PPARD | Q03181 | 7/20 | 0.50 |
| ▸ | PPARA | Q07869 | 7/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL230983 | 1.00 | LMNA (0.58) | LMNATSHRNFKB1PMP22GPR84 | |
| SCHEMBL29227501 | 0.97 | TSHR (0.60) | LMNATSHRNFKB1PMP22GPR84 | |
| SCHEMBL30302267 | 0.97 | TSHR (0.60) | LMNATSHRNFKB1PMP22GPR84 | |
| Azelaic Acid SCHEMBL8594583 | 0.97 | TSHR (0.60) | LMNATSHRNFKB1PMP22GPR84 | |
| Sebacic Acid SCHEMBL11387993 | 0.97 | TSHR (0.60) | LMNATSHRNFKB1PMP22GPR84 | |
| Octanedioate SCHEMBL31742463 | 0.97 | TSHR (0.60) | LMNATSHRNFKB1PMP22GPR84 | |
| Pimelic Acid SCHEMBL30288546 | 0.97 | TSHR (0.60) | LMNATSHRNFKB1PMP22GPR84 | |
| Adipic Acid SCHEMBL31052920 | 0.95 | LMNA (0.52) | LMNATSHRNFKB1PMP22GPR84 | |
| Adipic Acid SCHEMBL21834595 | 0.95 | GPR84 (0.54) | LMNATSHRNFKB1PMP22GPR84 | |
| Glutarate SCHEMBL28715418 | 0.95 | SLC22A6 (0.58) | LMNATSHRNFKB1PMP22GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7641991-B2 | Magnetic recording medium | FUJIFILM CORPORATION (JP) | 2010-01-05 | — | — | US | disclosed |
| US-20070065684-A1 | Magnetic recording medium | FUJI PHOTO FILM CO., LTD. | 2007-03-22 | — | — | US | disclosed |
| US-4996243-A | 2-Alkenyl-5,6-dihydro-4H-1,3-oxazin-6-one-modified polymers and a photoinitiator; adhesives; films; inks; coatings; and saturants | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-02-26 | — | — | US | disclosed |
| US-4914223-A | Coatings, films, printing inks, adhesives | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-04-03 | — | — | US | disclosed |
| US-4851294-A | DIUREA REACTION PRODUCT OF DIISOCYANATE AND PRIMARY AMINE COMPOUND CONTAINING ETHER GROUP | AKZO N.V. (NL) | 1989-07-25 | — | — | US | disclosed |
| US-4837290-A | REACTING ALKENYL AZLACTONE WITH POLYMER | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-06-06 | — | — | US | disclosed |
| US-4777276-A | COATINGS, FILMS, PRINTING INKS AND ADHESIVES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-10-11 | — | — | US | disclosed |
| EP-0091956-B1 | ACRYLAMIDOACYLATED OLIGOMERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1986-02-26 | — | — | EP | disclosed |
| EP-0091956-A4 | ACRYLAMIDOACYLATED OLIGOMERS. | MINNESOTA MINING & MFG (US) | 1984-04-24 | — | — | EP | disclosed |
| EP-0091956-A1 | ACRYLAMIDOACYLATED OLIGOMERS. | MINNESOTA MINING & MFG (US) | 1983-10-26 | — | — | EP | disclosed |
| WO-1983001617-A1 | ACRYLAMIDOACYLATED OLIGOMERS | MINNESOTA MINING & MFG (US) | 1983-05-11 | — | — | WO | disclosed |