Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 7/20 | 0.50 |
| ▸ | PPARD | Q03181 | 7/20 | 0.50 |
| ▸ | PPARA | Q07869 | 7/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL3475386 | 1.00 | LMNA (0.58) | LMNATSHRNFKB1PMP22GPR84 | |
| SCHEMBL29227501 | 0.97 | TSHR (0.60) | LMNATSHRNFKB1PMP22GPR84 | |
| SCHEMBL30302267 | 0.97 | TSHR (0.60) | LMNATSHRNFKB1PMP22GPR84 | |
| Azelaic Acid SCHEMBL8594583 | 0.97 | TSHR (0.60) | LMNATSHRNFKB1PMP22GPR84 | |
| Sebacic Acid SCHEMBL11387993 | 0.97 | TSHR (0.60) | LMNATSHRNFKB1PMP22GPR84 | |
| Octanedioate SCHEMBL31742463 | 0.97 | TSHR (0.60) | LMNATSHRNFKB1PMP22GPR84 | |
| Pimelic Acid SCHEMBL30288546 | 0.97 | TSHR (0.60) | LMNATSHRNFKB1PMP22GPR84 | |
| Adipic Acid SCHEMBL31052920 | 0.95 | LMNA (0.52) | LMNATSHRNFKB1PMP22GPR84 | |
| Adipic Acid SCHEMBL21834595 | 0.95 | GPR84 (0.54) | LMNATSHRNFKB1PMP22GPR84 | |
| Glutarate SCHEMBL28715418 | 0.95 | SLC22A6 (0.58) | LMNATSHRNFKB1PMP22GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2152 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122037853-A | Steam-skinning-resistant PUR edge sealing adhesive modified material and preparation method thereof | 佛山市极威新材料有限公司 | 2026-05-15 | — | — | CN | claimed |
| EP-4237605-B1 | MELT-SPUN THERMOPLASTIC POLYURETHANE FIBER | LUBRIZOL ADVANCED MAT INC (US) | 2026-04-01 | — | — | EP | claimed |
| EP-4237604-B1 | DYEABLE FABRIC COMPRISING MELT-SPUN THERMOPLASTIC POLYURETHANE FIBERS | LUBRIZOL ADVANCED MAT INC (US) | 2026-03-25 | — | — | EP | claimed |
| CN-121572687-A | Layered flame-retardant polyurethane composite material and preparation method thereof | 深圳市力信陆南实业有限公司 | 2026-02-27 | — | — | CN | claimed |
| US-12552970-B2 | Adhesive sheet, construct, and method for producing construct | LINTEC CORPORATION (JP) | 2026-02-17 | — | — | US | claimed |
| US-12515378-B2 | Method of making articles from recyclable fabrics | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2026-01-06 | — | — | US | claimed |
| US-20250361653-A1 | DYEABLE FABRIC COMPRISING MELT-SPUN THERMOPLASTIC POLYURETHANE FIBERS | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2025-11-27 | — | — | US | claimed |
| EP-3892258-B1 | COMPOSITION CONTAINING WATER-SOLUBLE NON-IONIC POLYURETHANE DISPERSION, AND PREPARATION METHOD THEREFOR | WANHUA CHEMICAL GROUP CO LTD (CN) | 2025-10-22 | — | — | EP | claimed |
| US-12404608-B2 | Dyeable fabric comprising melt-spun thermoplastic polyurethane fibers | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2025-09-02 | — | — | US | claimed |
| CN-120118652-A | Water-based single-component adhesive for spraying and preparation method and application thereof | 万华化学集团股份有限公司 | 2025-06-10 | — | — | CN | claimed |
| US-5989527-A | Compositions and methods for improving the performance of chemical exfoliating agents, sunless tanning agents, skin lightening agents and insect repellents | INOLEX INVESTMENT CORPORATION (US) | 1999-11-23 | — | — | US | claimed |
| EP-0709737-A1 | Radiation curable adhesive | EASTMAN KODAK COMPANY (US) | 1996-05-01 | — | — | EP | claimed |
| US-5466723-A | Acrylic ester monomers, acrylated polyesterurethane | EASTMAN KODAK COMPANY (US) | 1995-11-14 | — | — | US | claimed |
| EP-0627451-A2 | Moisture curable, plasticized polyurethane adhesives | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-12-07 | — | — | EP | claimed |
| US-5221581-A | For finishing or maintaining finishes of automobile or truck exteriors | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-06-22 | — | — | US | claimed |
| EP-0525578-A1 | Photopolymer composition for the production of three-dimensional objects | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-02-03 | — | — | EP | claimed |
| EP-0373671-A2 | Waterborne polyurethane dispersions | SANNCOR INDUSTRIES, INC. (US) | 1990-06-20 | — | — | EP | claimed |
| US-4703338-A | Resin composition to seal electronic device | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1987-10-27 | — | — | US | claimed |
| US-4346201-A | COATINGS FOR FLEXIBLE SUBSTRATES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-08-24 | — | — | US | claimed |
| US-3994851-A | AMINE-ALDEHYDE CROSSLINKING AGENT | PPG INDUSTRIES, INC. (US) | 1976-11-30 | — | — | US | claimed |