Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.73 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30173483 | 0.86 | PPARG (0.67) | PPARG | |
| SCHEMBL12177160 | 0.84 | PPARG (0.70) | PPARGCISD1AKR1B1ENPP2 | |
| SCHEMBL12177142 | 0.83 | PPARG (0.63) | PPARGENPP2 | |
| SCHEMBL6686160 | 0.82 | PPARG (0.77) | PPARGENPP2 | |
| SCHEMBL6686162 | 0.82 | PPARG (0.77) | PPARGENPP2 | |
| SCHEMBL12177161 | 0.82 | PPARG (0.64) | PPARGCISD1AKR1B1ENPP2 | |
| SCHEMBL30173484 | 0.81 | MAPK1 (0.70) | PPARGAKR1B1 | |
| SCHEMBL12177171 | 0.80 | PPARG (0.71) | PPARGAKR1B1ENPP2 | |
| SCHEMBL12177785 | 0.80 | PIM1 (0.56) | PPARGCISD1AKR1B1ENPP2 | |
| SCHEMBL12177385 | 0.80 | ENPP2 (0.71) | PPARGENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4142795-A1 | PPAR? AGONISTS FOR TREATMENT OF KIDNEY DISEASE | The Research Institute at Nationwide Children's Hospital (US) | 2023-03-08 | — | — | EP | disclosed |