Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | CRHBP | P24387 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.63 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30173484 | 0.91 | MAPK1 (0.70) | PPARGMAPK1MEN1ALDH1A1POLB | |
| SCHEMBL30173481 | 0.86 | PPARG (0.73) | PPARG | |
| SCHEMBL6692200 | 0.80 | PPARG (0.68) | PPARGMAPK1MEN1ALDH1A1POLB | |
| SCHEMBL6692202 | 0.80 | PPARG (0.68) | PPARGMAPK1MEN1ALDH1A1POLB | |
| SCHEMBL15816886 | 0.80 | PPARG (0.60) | PPARGMAPK1 | |
| SCHEMBL15816888 | 0.80 | PPARG (0.60) | PPARGMAPK1 | |
| SCHEMBL15816884 | 0.80 | PPARG (0.60) | PPARGMAPK1 | |
| SCHEMBL12177160 | 0.80 | PPARG (0.70) | PPARGNPSR1 | |
| SCHEMBL5470020 | 0.79 | MAPK1 (0.85) | MAPK1MEN1ALDH1A1POLBMAPT | |
| SCHEMBL5470014 | 0.79 | MAPK1 (0.85) | MAPK1MEN1ALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4142795-A1 | PPAR? AGONISTS FOR TREATMENT OF KIDNEY DISEASE | The Research Institute at Nationwide Children's Hospital (US) | 2023-03-08 | — | — | EP | disclosed |