Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 10/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 9/20 | 0.49 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.44 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.43 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27893425 | 0.84 | CYP3A4 (0.51) | CYP3A4CYP2C19LMNACYP1A2MKNK1 | |
| SCHEMBL30174277 | 0.78 | CHEK2 (0.46) | CHEK2CYP2A6IKBKBBTK | |
| SCHEMBL29812074 | 0.78 | SQOR (0.43) | MKNK1MKNK2CHEK2IKBKBSLC22A12 | |
| SCHEMBL30174307 | 0.77 | IKBKB (0.45) | LMNACYP1A2MKNK1MKNK2CHEK2 | |
| SCHEMBL30174177 | 0.75 | TOP2A (0.41) | CYP3A4CYP2C19LMNACYP1A2MKNK1 | |
| SCHEMBL30174280 | 0.73 | IKBKB (0.43) | CYP2C19CYP1A2IKBKB | |
| SCHEMBL16487155 | 0.73 | CYP3A4 (0.42) | CYP3A4CYP2C19LMNACYP1A2MKNK1 | |
| SCHEMBL14917436 | 0.73 | CHEK2 (0.52) | CYP3A4CYP2C19LMNACYP1A2MKNK1 | |
| SCHEMBL945200 | 0.73 | MKNK1 (0.51) | CYP3A4CYP2C19LMNACYP1A2MKNK1 | |
| SCHEMBL18426271 | 0.72 | CYP1A2 (0.52) | CYP3A4CYP2C19LMNACYP1A2MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605478-A | Compounds and methods of use | 埃克塞里艾克西斯公司（US） | 2023-01-13 | — | — | CN | disclosed |