Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 5/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.33 |
| ▸ | NNMT | P40261 | 2/20 | 0.33 |
| ▸ | SLC34A1 | Q06495 | 2/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30174180 | 0.88 | GABRA5 (0.36) | GABRA5JAK1TYK2GRM5NPC1 | |
| SCHEMBL25237940 | 0.88 | GABRA5 (0.36) | GABRA5JAK1TYK2GRM5NPC1 | |
| SCHEMBL29812239 | 0.83 | MAPT (0.42) | NPC1CASP3RAB9ASMN1; SMN2SENP8 | |
| SCHEMBL29812433 | 0.79 | LRRK2 (0.38) | PTPN11NNMTLRRK2 | |
| SCHEMBL30761120 | 0.73 | LCK (0.37) | PTPN11SQOR | |
| SCHEMBL29812395 | 0.72 | MAPT (0.47) | NPC1RAB9ASMN1; SMN2LRRK2KDM4E | |
| SCHEMBL29812688 | 0.70 | MAPT (0.40) | NPC1CASP3RAB9ASMN1; SMN2SENP8 | |
| SCHEMBL23147598 | 0.70 | MAPT (0.40) | NPC1CASP3RAB9ASMN1; SMN2SENP8 | |
| SCHEMBL29812726 | 0.69 | LRRK2 (0.42) | NPC1RAB9ALRRK2KDM4EALDH1A1 | |
| SCHEMBL30174202 | 0.68 | TGFBR1 (0.38) | GABRA5JAK1TYK2HPGDSNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605478-A | Compounds and methods of use | 埃克塞里艾克西斯公司（US） | 2023-01-13 | — | — | CN | disclosed |