Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.46 |
| ▸ | HTR3B | O95264 | 3/20 | 0.46 |
| ▸ | HTR3A | P46098 | 3/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | AGXT | P21549 | 2/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25209309 | 1.00 | PNMT (0.48) | PNMTHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL25518220 | 0.93 | PNMT (0.46) | PNMTHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL31374947 | 0.93 | SLC6A4 (0.46) | PNMTHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL25517176 | 0.77 | OPRL1 (0.46) | TAAR1IDO1OPRL1 | |
| SCHEMBL2473095 | 0.77 | MAOA (0.59) | PNMTHTR3EHTR3BHTR3AHTR3D | |
| Hydrochloric Acid SCHEMBL21879608 | 0.76 | MAOB (0.57) | PNMTHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL28960982 | 0.75 | GRIN2D (0.51) | TAAR1IDO1CYP3A4OPRL1SLC6A2 | |
| SCHEMBL30601825 | 0.75 | HSD11B1 (0.51) | PNMTHSD11B1SIGMAR1EPHX2 | |
| SCHEMBL26123313 | 0.75 | HSD11B1 (0.51) | PNMTHSD11B1SIGMAR1EPHX2 | |
| SCHEMBL23343753 | 0.74 | OPRL1 (0.65) | OPRL1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4132944-A1 | INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION | Cocrystal Pharma, Inc. (US) | 2023-02-15 | — | — | EP | disclosed |