SCHEMBL30175604

SCHEMBL30175604

CC(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)c(F)c1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CXCR2 P25025 2/20 0.38
ALDH1A1 P00352 3/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
KDM4E B2RXH2 1/20 0.36
LPL P06858 1/20 0.36
LIPG Q9Y5X9 1/20 0.36
ROCK1 Q13464 1/20 0.35
KIF11 P52732 1/20 0.35
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
NPC1 O15118 2/20 0.34
MAPT P10636 2/20 0.34
RAB9A P51151 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
HPGD P15428 2/20 0.34
HTT P42858 1/20 0.34
P4HB P07237 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19318869 1.00 CXCR2 (0.38) CXCR2ALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL29528340 0.88 LMNA (0.45) CXCR2KDM4ELPLLIPGROCK1
SCHEMBL1130939 0.88 LMNA (0.45) CXCR2KDM4ELPLLIPGROCK1
SCHEMBL2645306 0.88 KDM4E (0.36) CXCR2ALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL20995735 0.86 CXCR2 (0.38) CXCR2LPLLIPGROCK1CES2
SCHEMBL1674267 0.86 PARP1 (0.38) CXCR2LPLLIPGROCK1CES2
SCHEMBL25064009 0.84 LPL (0.36) CXCR2LPLLIPGROCK1
SCHEMBL17235879 0.84 CXCR2 (0.43) CXCR2ALDH1A1SMN1; SMN2KDM4ELPL
SCHEMBL12068196 0.84 ERN1 (0.37) CXCR2ALDH1A1SMN1; SMN2LPLLIPG
SCHEMBL30963854 0.84 CA12 (0.41) CXCR2ALDH1A1MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025106910-A1 DEGRADER MOLECULES TARGETING ANDROGEN RECEPTOR FLARE THERAPEUTICS INC. (US) 2025-05-22 WO disclosed
EP-4081215-A1 METHODS AND COMPOSITIONS FOR INHIBITION OF DIHYDROOROTATE DEHYDROGENASE Ohio State Innovation Foundation (US) 2022-11-02 EP disclosed