Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.36 |
| ▸ | LPL | P06858 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30316304 | 0.88 | LMNA (0.41) | KDM4EMEN1KMT2ACXCR2LPL | |
| SCHEMBL19318869 | 0.88 | CXCR2 (0.38) | KDM4EMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL30175604 | 0.88 | CXCR2 (0.38) | KDM4EMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL20605342 | 0.86 | PARP1 (0.41) | CXCR2LPLLIPGROCK1LIPE | |
| SCHEMBL15056446 | 0.84 | MAPT (0.42) | MEN1ALDH1A1KMT2ASMN1; SMN2CXCR2 | |
| SCHEMBL938124 | 0.84 | CA12 (0.41) | KDM4EMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL18371630 | 0.83 | PKM (0.44) | KDM4ENPC1MAPTRAB9AP4HB | |
| SCHEMBL14217297 | 0.83 | CYP2A6 (0.38) | KDM4EMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL18748515 | 0.81 | KIF11 (0.44) | ALDH1A1KMT2ASMN1; SMN2MAOBMAOA | |
| SCHEMBL21928331 | 0.81 | MEN1 (0.42) | KDM4EMEN1ALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116425782-A | Preparation method of 5-acetyl-2-fluorobenzeneboronic acid pinacol ester | 烟台盛凯伦化学科技有限公司 | 2023-07-14 | — | — | CN | claimed |
| CN-116425782-A | Preparation method of 5-acetyl-2-fluorobenzeneboronic acid pinacol ester | 烟台盛凯伦化学科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-116425782-A | Preparation method of 5-acetyl-2-fluorobenzeneboronic acid pinacol ester | 烟台盛凯伦化学科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-116425782-A | Preparation method of 5-acetyl-2-fluorobenzeneboronic acid pinacol ester | 烟台盛凯伦化学科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| EP-2858982-A1 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES | AbbVie Inc. (US) | 2015-04-15 | — | — | EP | disclosed |
| EP-2858990-A1 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES | AbbVie Inc. (US) | 2015-04-15 | — | — | EP | disclosed |
| WO-2013188381-A1 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES | ABBVIE INC. (US) | 2013-12-19 | — | — | WO | disclosed |
| WO-2013185284-A1 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES | ABBOTT LABORATORIES (US) | 2013-12-19 | — | — | WO | disclosed |
| US-6969716-B2 | 5-phenyl[1,2,4]triazines as ligands for GABA-A α2/α3 receptors for treating anxiety or depression | MERCK SHARP & DOHME LTD. | 2005-11-29 | — | — | US | disclosed |
| US-20040192692-A1 | 5-Phenyl[1,2,4]triazines as ligands for GABA-A alpha2/alpha3 receptors for treating anxiety or depression | MERCK SHARP & DOHME, LTD. (GB) | 2004-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192692-A1 | 5-Phenyl[1,2,4]triazines as ligands for GABA-A alpha2/alpha3 receptors for treating anxiety or depression | GABRA1, GABRA5, GABRA2 | KDM4E 3163/4885MEN1 4325/4885ALDH1A1 260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.