SCHEMBL30178189

SCHEMBL30178189

NCCCC[C@@H](NC(=O)[C@@H](CCC(=O)O)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)Cc1ccc(O)cc1)C(N)=O

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ LNPEP Q9UIQ6 2/20 0.51
▸ ERAP2 Q6P179 1/20 0.51
▸ NPY4R P50391 4/20 0.50
▸ NPY1R P25929 3/20 0.50
▸ NPY2R P49146 3/20 0.50
▸ NPY5R Q15761 2/20 0.50
▸ NAALAD2 Q9Y3Q0 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31025663 0.93 LNPEP (0.59) LNPEPERAP2NPY4RNPY1RNPY2R
SCHEMBL31710294 0.93 LNPEP (0.59) LNPEPERAP2NPY4RNPY1RNPY2R
SCHEMBL29972888 0.91 MMP2 (0.52) LNPEPERAP2
SCHEMBL29868753 0.91 LNPEP (0.55) LNPEPERAP2NPY4RNPY1RNPY2R
SCHEMBL25627390 0.88 CHRND (0.50) NPY4RNPY1RNPY2RNPY5RNAALAD2
SCHEMBL30688840 0.87 GHSR (0.51) LNPEPERAP2
SCHEMBL30090915 0.87 LNPEP (0.64) LNPEPERAP2NPY4RNPY1RNPY2R
SCHEMBL285712 0.86 NAALAD2 (0.58) LNPEPERAP2NPY4RNPY1RNPY2R
SCHEMBL29854734 0.86 NAALAD2 (0.58) LNPEPERAP2NPY4RNPY1RNPY2R
SCHEMBL31710009 0.86 NAALAD2 (0.58) LNPEPERAP2NPY4RNPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4676599-A1 IMPROVED BISPECIFIC ANTI-TUMOR ANTIGEN/ANTI-HSG ANTIBODIES FOR PRE-TARGETING OF HYPERPROLIFERATIVE DISORDERS OncoOne Research & Development GmbH (AT) 2026-01-14 — — EP disclosed
EP-4396227-B1 IMPROVED FC SILENCED ANTI-OXMIF ANTIBODIES WITH REDUCED AGGREGATION POTENTIAL AND REDUCED HYDROPHOBICITY ONCOONE RES & DEVELOPMENT GMBH (AT) 2025-07-09 — — EP disclosed
US-20250129148-A1 IMPROVED Fc SILENCED ANTI-oxMIF ANTIBODIES WITH REDUCED AGGREGATION POTENTIAL AND REDUCED HYDROPHOBICITY ONCOONE RESEARCH & DEVELOPMENT GMBH (AT) 2025-04-24 — — US disclosed
WO-2024184171-A1 IMPROVED BISPECIFIC ANTI-TUMOR ANTIGEN/ANTI-HSG ANTIBODIES FOR PRE-TARGETING OF HYPERPROLIFERATIVE DISORDERS ONCOONE RESEARCH & DEVELOPMENT GMBH (AT) 2024-09-12 — — WO disclosed
EP-4396227-A1 IMPROVED FC SILENCED ANTI-OXMIF ANTIBODIES WITH REDUCED AGGREGATION POTENTIAL AND REDUCED HYDROPHOBICITY OncoOne Research & Development GmbH (AT) 2024-07-10 — — EP disclosed
CN-118302444-A Improved Fc-silenced anti-oxMIF antibodies with reduced aggregation potential and reduced hydrophobicity 翁科奥内研发有限责任公司 2024-07-05 — — CN disclosed
WO-2023031397-A1 IMPROVED Fc SILENCED ANTI-oxMIF ANTIBODIES WITH REDUCED AGGREGATION POTENTIAL AND REDUCED HYDROPHOBICITY ONCOONE RESEARCH & DEVELOPMENT GMBH (AT) 2023-03-09 — — WO disclosed
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