Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21900226 | 0.86 | CDK9 (0.41) | CDK9ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL21900263 | 0.79 | CDK9 (0.44) | CDK9ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL17870749 | 0.78 | CDK9 (0.40) | CDK9ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL17870748 | 0.76 | CDK9 (0.39) | CDK9ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL17870821 | 0.76 | CDK9 (0.42) | CDK9ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL19873909 | 0.76 | ALDH1A1 (0.39) | CDK9ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL21900243 | 0.76 | ALDH1A1 (0.35) | CDK9ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL21900244 | 0.76 | ALDH1A1 (0.35) | CDK9ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL30178325 | 0.75 | GNRHR (0.46) | — | |
| SCHEMBL17870770 | 0.74 | CDK9 (0.41) | CDK9ALDH1A1KDM4EPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3708566-B1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2023-02-08 | — | — | EP | disclosed |