Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17870748 | 0.92 | CDK9 (0.39) | CDK9ADORA2BLMNAKDM4EALDH1A1 | |
| SCHEMBL28639222 | 0.85 | CDK9 (0.40) | CDK9KDM4EALDH1A1POLBMAPT | |
| SCHEMBL17870821 | 0.84 | CDK9 (0.42) | CDK9ADORA2BLMNAKDM4EALDH1A1 | |
| SCHEMBL17870770 | 0.82 | CDK9 (0.41) | CDK9ADORA2BLMNAKDM4EALDH1A1 | |
| SCHEMBL21900263 | 0.81 | CDK9 (0.44) | CDK9ADORA2BLMNAKDM4EALDH1A1 | |
| SCHEMBL17870758 | 0.81 | ALDH1A1 (0.41) | CDK9ADORA2BLMNAKDM4EALDH1A1 | |
| SCHEMBL19873978 | 0.80 | ALDH1A1 (0.35) | CDK9ADORA2BALDH1A1 | |
| SCHEMBL17870781 | 0.80 | CDK9 (0.39) | CDK9ADORA2BLMNAKDM4EALDH1A1 | |
| SCHEMBL17870817 | 0.78 | CDK9 (0.41) | CDK9ADORA2BLMNAKDM4EALDH1A1 | |
| SCHEMBL30178741 | 0.78 | CDK9 (0.39) | CDK9ADORA2BLMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3708566-B1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2023-02-08 | — | — | EP | disclosed |
| EP-3708566-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2020-09-16 | — | — | EP | disclosed |
| EP-3237403-B1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2020-05-06 | — | — | EP | disclosed |
| EP-3237403-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2017-11-01 | — | — | EP | disclosed |
| WO-2016102882-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2016-06-30 | — | — | WO | disclosed |