Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 20/20 | 0.84 |
| ▸ | CYP2C9 | P11712 | 14/20 | 0.84 |
| ▸ | CYP2D6 | P10635 | 13/20 | 0.84 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.68 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.58 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.58 |
| ▸ | AR | P10275 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3024866 | 0.92 | PGR (0.83) | PGRCYP2C9CYP2D6KCNH2 | |
| SCHEMBL3026798 | 0.91 | PGR (0.70) | PGRCYP2C9CYP2D6KCNH2 | |
| SCHEMBL3035009 | 0.91 | PGR (1.00) | PGRCYP2C9CYP2D6KCNH2NR3C1 | |
| SCHEMBL3028034 | 0.91 | PGR (0.87) | PGRCYP2C9CYP2D6KCNH2NR3C1 | |
| SCHEMBL5030156 | 0.91 | PGR (1.00) | PGRCYP2C9CYP2D6KCNH2NR3C1 | |
| SCHEMBL3035899 | 0.90 | PGR (0.82) | PGRCYP2C9CYP2D6KCNH2NR3C1 | |
| SCHEMBL3034111 | 0.90 | PGR (0.84) | PGRCYP2C9CYP2D6KCNH2NR3C1 | |
| SCHEMBL3031484 | 0.89 | PGR (0.82) | PGRCYP2C9CYP2D6KCNH2 | |
| SCHEMBL3029774 | 0.88 | PGR (0.79) | PGRCYP2C9CYP2D6KCNH2NR3C1 | |
| SCHEMBL3035989 | 0.88 | PGR (0.82) | PGRCYP2C9CYP2D6KCNH2NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216813-A1 | PYRROLIDINEANILINES | SMITHKLINE BEECHAM CORPORATION | 2010-08-26 | — | — | US | disclosed |
| US-20100216813-A1 | PYRROLIDINEANILINES | SMITHKLINE BEECHAM CORPORATION | 2010-08-26 | — | — | US | disclosed |
| US-20100216813-A1 | PYRROLIDINEANILINES | SMITHKLINE BEECHAM CORPORATION | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216813-A1 | PYRROLIDINEANILINES | PGF, ARG1, CYP19A1 | PGR 11/4885CYP2C9 2288/4885CYP2D6 2630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.