SCHEMBL30179538

SCHEMBL30179538

CCCCC(NC(=O)CCSSc1ccccn1)C(=O)ON1C(=O)CC(S(=O)(=O)O)C1=O

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 14/20 0.39
HDAC2 Q92769 13/20 0.39
REN P00797 2/20 0.32
HDAC4 P56524 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6034749 0.86 HDAC1 (0.44) HDAC1HDAC2HDAC6
SCHEMBL5958158 0.83 HDAC1 (0.33) HDAC1HDAC2
SCHEMBL30367749 0.80 ALDH1A1 (0.36) HDAC1HDAC2HDAC4HDAC6L3MBTL1
SCHEMBL5485914 0.80 ALDH1A1 (0.36) HDAC1HDAC2HDAC4HDAC6L3MBTL1
SCHEMBL29427565 0.80 HDAC1 (0.34) HDAC1HDAC2HDAC4HDAC6
SCHEMBL29361373 0.79 HPGD (0.37) HDAC1HDAC2HDAC4HDAC6
SCHEMBL44111 0.79 HPGD (0.37) HDAC1HDAC2HDAC4HDAC6
SCHEMBL16047481 0.79 HDAC1 (0.36) HDAC1HDAC2HDAC4HDAC6
SCHEMBL29840661 0.78 TAS1R3 (0.32) HDAC2
SCHEMBL12056750 0.78 HPGD (0.36) HDAC1HDAC2HDAC4HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4687843-A1 FORMULATIONS AND USES THEREOF Sartorius Albumedix Limited (GB) 2026-02-11 EP disclosed
US-12116400-B2 Albumin variants and conjugates SARTORIUS ALBUMEDIX LIMITED (GB) 2024-10-15 US disclosed
WO-2024209085-A1 FORMULATIONS AND USES THEREOF ALBUMEDIX LTD (GB) 2024-10-10 WO disclosed
EP-4442251-A1 FORMULATIONS AND USES THEREOF Albumedix Ltd (GB) 2024-10-09 EP disclosed
EP-3243835-B1 ALBUMIN VARIANTS AND CONJUGATES ALBUMEDIX LTD (GB) 2024-04-10 EP disclosed
EP-3337816-B1 ALBUMIN VARIANTS AND CONJUGATES ALBUMEDIX LTD (GB) 2024-02-14 EP disclosed
US-20230039076-A1 ALBUMIN VARIANTS AND CONJUGATES SARTORIUS ALBUMEDIX LIMITED (GB) 2023-02-09 US disclosed
US-11555061-B2 Albumin variants and conjugates ALBUMEDIX, LTD (GB) 2023-01-17 US disclosed