Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
| ▸ | HRH1 | P35367 | 4/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 6/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850657 | 0.98 | MAOA (0.58) | MAOAHRH1HTR2ACYP3A4IDO1 | |
| SCHEMBL5966793 | 0.93 | MAOA (0.50) | MAOAHRH1HTR2ACYP3A4IDO1 | |
| SCHEMBL3680378 | 0.87 | MAOA (0.75) | MAOAHRH1HTR2AMAOB | |
| SCHEMBL9350714 | 0.85 | MAOA (0.71) | MAOAHRH1HTR2AMAOB | |
| SCHEMBL168309 | 0.82 | TAAR1 (0.56) | HTR2ACYP3A4IDO1MAOB | |
| SCHEMBL5243221 | 0.82 | CYP3A4 (0.46) | HTR2ACYP3A4IDO1SPHK2SPHK1 | |
| SCHEMBL18551297 | 0.81 | MAOA (0.60) | MAOAHRH1HTR2AMAOB | |
| SCHEMBL3678682 | 0.79 | MAOA (0.62) | MAOAHRH1HTR2A | |
| SCHEMBL15352442 | 0.78 | SIGMAR1 (0.40) | CYP3A4IDO1SPHK2SPHK1MAOB | |
| SCHEMBL2328304 | 0.78 | MAOB (0.67) | MAOAHRH1HTR2ACYP3A4MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4146268-A2 | METHODS OF DETECTING AND TREATING LUNG DAMAGE IN RESPIRATORY-RELATED VIRAL INFECTIONS | The Regents of the University of California (US) | 2023-03-15 | — | — | EP | disclosed |