Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 9/20 | 0.56 |
| ▸ | HTR2A | P28223 | 4/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HTR3A | P46098 | 1/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL224548 | 0.85 | TAAR1 (0.72) | TAAR1HTR2ACYP2A6CYP1A2KDM4E | |
| SCHEMBL5966793 | 0.84 | MAOA (0.50) | TAAR1HTR2ACYP2A6CYP1A2CYP3A4 | |
| SCHEMBL6049447 | 0.83 | TAAR1 (0.42) | TAAR1HTR2ACYP2A6CYP1A2KDM4E | |
| SCHEMBL30180481 | 0.82 | MAOA (0.60) | HTR2AMAOBCYP3A4IDO1 | |
| Hydrochloric Acid SCHEMBL3168355 | 0.82 | BLM (0.74) | TAAR1HTR2ACYP2A6CYP1A2KDM4E | |
| SCHEMBL6510298 | 0.82 | CYP3A4 (0.50) | CYP1A2CYP3A4IDO1 | |
| SCHEMBL2355588 | 0.82 | CYP3A4 (0.50) | CYP1A2CYP3A4IDO1 | |
| Hydrochloric Acid SCHEMBL3668004 | 0.82 | BLM (0.74) | TAAR1HTR2ACYP2A6CYP1A2KDM4E | |
| Iodide SCHEMBL29101247 | 0.82 | TAAR1 (0.68) | TAAR1HTR2ACYP2A6CYP1A2KDM4E | |
| SCHEMBL9850657 | 0.80 | MAOA (0.58) | HTR2ACYP3A4IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117801815-B | Chiral quasi two-dimensional perovskite film capable of emitting circularly polarized light and preparation method thereof | 天津大学 | 2024-08-09 | — | — | CN | claimed |
| CN-117801815-A | Chiral quasi two-dimensional perovskite film capable of emitting circularly polarized light and preparation method thereof | 天津大学 | 2024-04-02 | — | — | CN | claimed |
| CN-121735989-B | Method for catalyzing hydroboration reaction of nitrile compound | WEIFANG UNIVERSITY (CN) | 2026-05-26 | — | — | CN | disclosed |
| CN-117801815-B | Chiral quasi two-dimensional perovskite film capable of emitting circularly polarized light and preparation method thereof | 天津大学 | 2024-08-09 | — | — | CN | disclosed |
| US-20240252535-A1 | CELLULAR COMPOSITION FOR TREATMENT OF DISEASES, DISORDERS OR CONDITIONS AND METHOD OF USE | YZTHERAPEUTIC PERFORMANCE LTD. (IL) | 2024-08-01 | — | — | US | disclosed |
| US-20240140971-A1 | PSMA TARGETED RADIOHALOGENATED UREAS FOR CANCER RADIOTHERAPY | THE JOHNS HOPKINS UNIVERSTY | 2024-05-02 | — | — | US | disclosed |
| CN-117801815-A | Chiral quasi two-dimensional perovskite film capable of emitting circularly polarized light and preparation method thereof | 天津大学 | 2024-04-02 | — | — | CN | disclosed |
| WO-2023150899-A1 | CONJUGATES OF CHEMOTHERAPY AGENTS AND TISSUE-BINDING SMALL MOLECULES, COMPOSITIONS AND METHODS THEREOF | CANWELL BIOTECH LIMITED (CN) | 2023-08-17 | — | — | WO | disclosed |
| CN-111848494-B | Guanidine compounds and uses thereof | 伊谬诺米特医疗有限公司 | 2023-08-01 | — | — | CN | disclosed |
| EP-3131877-B1 | BIGUANIDE COMPOUNDS | IMMUNOMET THERAPEUTICS INC (US) | 2023-07-19 | — | — | EP | disclosed |
| US-11465989-B2 | Guanidine compounds and use thereof | ImmunoMet Therapeutics, Inc. (US) | 2022-10-11 | — | — | US | disclosed |
| WO-1995004072-A1 | PEPTOID ALPHA-1 ADRENERGIC RECEPTOR LIGANDS | CHIRON CORPORATION (US) | 1995-02-09 | — | — | WO | disclosed |
| WO-1994006451-A1 | SYNTHESIS OF N-SUBSTITUTED OLIGOMERS | CHIRON CORPORATION (US) | 1994-03-31 | — | — | WO | disclosed |
| US-5296483-A | Antidepressant | UNIVERSITY OF FLORIDA (US) | 1994-03-22 | — | — | US | disclosed |
| US-5082853-A | Drug delivery | BODOR NICHOLAS S (US) | 1992-01-21 | — | — | US | disclosed |
| US-4933438-A | Brain-specific analogues of centrally acting amines | UNIVERSITY OF FLORIDA (US) | 1990-06-12 | — | — | US | disclosed |
| EP-0174342-B1 | BRAIN-SPECIFIC ANALOGUES OF CENTRALLY ACTING AMINES | UNIVERSITY OF FLORIDA (US) | 1989-12-20 | — | — | EP | disclosed |
| US-4771059-A | CENTRAL NERVOUS SYSTEM | UNIVERSITY OF FLORIDA (US) | 1988-09-13 | — | — | US | disclosed |
| EP-0174342-A1 | BRAIN-SPECIFIC ANALOGUES OF CENTRALLY ACTING AMINES. | UNIV FLORIDA (US) | 1986-03-19 | — | — | EP | disclosed |
| WO-1985003937-A1 | BRAIN-SPECIFIC ANALOGUES OF CENTRALLY ACTING AMINES | UNIVERSITY OF FLORIDA (US) | 1985-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11465989-B2 | Guanidine compounds and use thereof | PC, TFAM, PCK2 | TAAR1 4576/4885HTR2A 3793/4885CYP2A6 2890/4885 |
| US-20240140971-A1 | PSMA TARGETED RADIOHALOGENATED UREAS FOR CANCER RADIOTHERAPY | PSMA3, PSMA6, PSMA7 | TAAR1 1397/4885HTR2A 4550/4885CYP2A6 3025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.