Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29008030 | 1.00 | KRAS (0.39) | KRASCHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL29008032 | 1.00 | KRAS (0.39) | KRASCHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL30181375 | 0.84 | CHRNB4 (0.39) | CHRNB4CHRNA3CHRNB2CHRNA4HTR1A | |
| SCHEMBL30181360 | 0.82 | CHRNB4 (0.38) | CHRNB4CHRNA3CHRNB2CHRNA4HTR1A | |
| SCHEMBL370789 | 0.79 | FFAR2 (0.38) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29007768 | 0.74 | CHRNA3 (0.64) | CHRNB4CHRNA3CHRNB2CHRNA4SLC6A2 | |
| SCHEMBL30181347 | 0.74 | CHRNA3 (0.64) | CHRNB4CHRNA3CHRNB2CHRNA4SLC6A2 | |
| Hydrochloric Acid SCHEMBL30417464 | 0.73 | CHRNA3 (0.62) | CHRNB4CHRNA3CHRNB2CHRNA4SLC6A2 | |
| SCHEMBL16175485 | 0.70 | SSTR4 (0.41) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29007796 | 0.69 | IRAK4 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157392-A | Compounds targeting RNA binding proteins or RNA modification proteins | 雷多纳治疗公司 | 2023-05-23 | — | — | CN | disclosed |
| EP-4114831-A1 | COMPOUNDS TARGETING RNA-BINDING PROTEINS OR RNA-MODIFYING PROTEINS | Twentyeight-Seven, Inc. (US) | 2023-01-11 | — | — | EP | disclosed |