Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 2/20 | 0.45 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312837 | 1.00 | TSHR (0.47) | TSHRMYCESR1ALOX15PTPN7 | |
| SCHEMBL5354014 | 0.85 | TSHR (0.45) | TSHRMYCESR1ALOX15PTPN7 | |
| SCHEMBL29528380 | 0.85 | TAS2R14 (0.50) | TSHRMYCESR1ALOX15PTPN7 | |
| SCHEMBL374174 | 0.85 | TAS2R14 (0.50) | TSHRMYCESR1ALOX15PTPN7 | |
| SCHEMBL312657 | 0.85 | KIF11 (0.56) | MEN1CYP1A2KMT2AKIF11NOTUM | |
| SCHEMBL18275139 | 0.84 | TSHR (0.44) | TSHRMYCESR1ALOX15PTPN7 | |
| SCHEMBL171490 | 0.83 | AR (0.45) | CYP1A2KIF11NOTUMALDH1A1 | |
| SCHEMBL15385132 | 0.83 | NOTUM (0.42) | MEN1CYP1A2KMT2ARXRARXRB | |
| SCHEMBL5214177 | 0.82 | EPHX2 (0.49) | TSHRMYCESR1ALOX15PTPN7 | |
| SCHEMBL31319449 | 0.82 | RXRA (0.48) | TSHRTTRRXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116003309-B | Hydrazide compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-116003309-A | Hydrazide compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-04-25 | — | — | CN | disclosed |
| WO-2023288253-A1 | SMALL MOLECULES INHIBITORS OF CYCLIC GMP-AMP SYNTHASE (CGAS) | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-01-19 | — | — | WO | disclosed |