SCHEMBL3018246

SCHEMBL3018246

C[C@H](CC(=O)O)NC(=O)OC(C)(C)C

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
CA7 P43166 1/20 0.51
CYP2D6 P10635 1/20 0.50
CTSK P43235 11/20 0.47
CTSS P25774 7/20 0.47
CTSL P07711 2/20 0.45
CTSB P07858 1/20 0.45
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
GAA P10253 1/20 0.42
ATM Q13315 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1372203 1.00 CA1 (0.51) CA1CA2CA7CYP2D6CTSK
SCHEMBL74360 1.00 CA1 (0.51) CA1CA2CA7CYP2D6CTSK
Alanine SCHEMBL9582963 0.92 CA1 (0.45) CA1CA2CA7CYP2D6CTSK
SCHEMBL4766284 0.87 CA1 (0.47) CA1CA2CA7CYP2D6CTSK
SCHEMBL25270811 0.85 CA1 (0.51) CA1CA2CA7CYP2D6CTSK
SCHEMBL5198000 0.85 CA1 (0.51) CA1CA2CA7CYP2D6CTSK
SCHEMBL27426180 0.85 CYP2D6 (0.63) CA1CA2CA7CYP2D6CTSK
SCHEMBL17616112 0.85 CA1 (0.51) CA1CA2CA7CYP2D6CTSK
SCHEMBL8972253 0.85 CYP2D6 (0.63) CA1CA2CA7CYP2D6CTSK
SCHEMBL28740911 0.84 CA1 (0.45) CA1CA2CA7CYP2D6CTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112876507-A Trisubstituted olefin tertiary phosphine compound and preparation method thereof 湖北大学 2021-06-01 CN claimed
EP-4736854-A2 HETEROCYCLIC COMPOUNDS AS MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS Bristol-Myers Squibb Company (US) 2026-05-06 EP disclosed
EP-4514473-B1 HETEROCYCLIC COMPOUNDS AS MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS BRISTOL MYERS SQUIBB CO (US) 2026-02-18 EP disclosed
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PEPTIDREAM INC (JP) 2026-01-15 US disclosed
EP-4655292-A1 NEW COMPOUNDS FOR TREATING STREPTOCOCCUS INFECTIONS Ab2 Therapeutics, S. L. (ES) 2025-12-03 EP disclosed
EP-4634184-A1 BIFUNCTIONAL COMPOUNDS FOR DEGRADING KINASES VIA UBIQUITIN PROTEOSOME PATHWAY Crossfire Oncology Holding B.V. (NL) 2025-10-22 EP disclosed
US-20250320183-A1 Modulators of BCL6 as Ligand Directed Degraders CELGENE CORPORATION (US) 2025-10-16 US disclosed
US-12404239-B2 Modulators of BCL6 as ligand directed degraders CELGENE CORPORATION (US) 2025-09-02 US disclosed
EP-4126861-B1 3-(ANILINO)-2-[3-(3-ALKOXY-PYRIDIN-4-YL]-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER BAYER AG (DE) 2025-06-18 EP disclosed
US-20250179075-A1 MK2 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2025-06-05 US disclosed
EP-0355331-A2 Poly(aminoalkyl)aminocarbonyl aminoacyl aminodiol amino acid derivatives as anti-hypertensive agents G.D. Searle & Co. (US) 1990-02-28 EP disclosed
US-4902706-A Aminoalkylaminocarbonyl aminodiol amino acid derivatives as antihypertensive agents G. D. SEARLE & CO. (US) 1990-02-20 US disclosed
US-4900746-A RENIN INHIBITORS G. D. SEARLE & CO. (US) 1990-02-13 US disclosed
WO-1990000052-A1 POLY(AMINOALKYL)AMINOCARBONYL AMINODIOL AMINO ACID DERIVATIVES AS ANTI-HYPERTENSIVE AGENTS G.D. SEARLE & CO. (US) 1990-01-11 WO disclosed
WO-1990000050-A1 AMINOALKYLAMINOCARBONYL AMINODIOL AMINO ACID DERIVATIVES AS ANTI-HYPERTENSIVE AGENTS G.D. SEARLE & CO. (US) 1990-01-11 WO disclosed
WO-1990000051-A1 ETHEREAL N-TERMINAL AMINODIOL AMINO ACID DERIVATIVES AS ANTI-HYPERTENSIVE AGENTS G.D. SEARLE & CO. (US) 1990-01-11 WO disclosed
EP-0349922-A2 Aminoalkylaminocarbonyl aminodiol amino acid derivatives as anti-hypertensive agents G.D. Searle & Co. (US) 1990-01-10 EP disclosed
EP-0349921-A2 Etheral n-terminal aminodiol amino acid derivatives as anti-hypertensive agents G.D. Searle & Co. (US) 1990-01-10 EP disclosed
US-4877785-A RENIN INHIBITORS G. D. SEARLE & CO. (US) 1989-10-31 US disclosed
EP-0310072-A2 Non-peptidyl beta-succinamidoacyl aminodiols as anti-hypertensive agents G.D. Searle & Co. (US) 1989-04-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF NSUN3, BCAT1, SLC43A1 CA1 2824/4885CA2 1024/4885CA7 1184/4885
US-12404239-B2 Modulators of BCL6 as ligand directed degraders BCL6, BCL6B, BCL3 CA1 3464/4885CA2 4634/4885CA7 3747/4885
US-20250320183-A1 Modulators of BCL6 as Ligand Directed Degraders BCL6, BCL6B, BCL3 CA1 3464/4885CA2 4634/4885CA7 3747/4885
US-20250179075-A1 MK2 DEGRADERS AND USES THEREOF MKNK2, MKRN3, DUS2 CA1 3568/4885CA2 2848/4885CA7 2048/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.