Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MELK | Q14680 | 2/20 | 0.69 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL531914 | 0.84 | NPC1 (0.66) | MELKSLC2A1NPC1RAB9ATP53 | |
| SCHEMBL24892142 | 0.79 | MELK (0.87) | MELKSLC2A1NPC1RAB9ATP53 | |
| SCHEMBL21798720 | 0.79 | KMT2A (0.76) | NPC1RAB9ATP53MEN1KMT2A | |
| SCHEMBL3679372 | 0.79 | KMT2A (0.76) | NPC1RAB9ATP53MEN1KMT2A | |
| SCHEMBL6497655 | 0.78 | MELK (0.50) | MELKSLC2A1 | |
| SCHEMBL30182258 | 0.77 | SLC2A1 (0.60) | MELKSLC2A1 | |
| SCHEMBL24891957 | 0.77 | SLC2A1 (0.60) | MELKSLC2A1 | |
| SCHEMBL24669402 | 0.76 | SLC2A1 (0.61) | MELKSLC2A1 | |
| SCHEMBL29803671 | 0.76 | SLC2A1 (0.61) | MELKSLC2A1 | |
| SCHEMBL12501320 | 0.75 | ITGB3 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |