SCHEMBL3018404

SCHEMBL3018404

CCCCOC(=O)COc1ccc(C(C)=O)cc1C

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.64
L3MBTL1 Q9Y468 2/20 0.57
ALDH1A1 P00352 2/20 0.57
TDP1 Q9NUW8 1/20 0.57
LMNA P02545 1/20 0.49
HPGD P15428 1/20 0.49
RAB9A P51151 1/20 0.49
ESR1 P03372 2/20 0.47
THRA P10827 1/20 0.47
THRB P10828 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.45
KDM4E B2RXH2 1/20 0.45
HSD17B10 Q99714 1/20 0.45
MAPT P10636 1/20 0.44
GAA P10253 1/20 0.44
WDR5 P61964 1/20 0.44
PPARG P37231 2/20 0.43
PPARD Q03181 2/20 0.43
PPARA Q07869 2/20 0.43
CYP1A2 P05177 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3019729 0.92 KMT2A (0.60) KMT2AL3MBTL1ALDH1A1TDP1HPGD
SCHEMBL2439155 0.88 KMT2A (0.57) KMT2AL3MBTL1ALDH1A1HPGDESR1
SCHEMBL12966511 0.87 THRA (0.58) L3MBTL1ESR1THRATHRBSMN1; SMN2
SCHEMBL4884515 0.85 ALDH1A1 (0.78) KMT2AL3MBTL1ALDH1A1TDP1LMNA
SCHEMBL3006259 0.84 ALDH1A1 (0.60) KMT2AL3MBTL1ALDH1A1TDP1LMNA
SCHEMBL3003375 0.83 ALDH1A1 (0.56) KMT2AL3MBTL1ALDH1A1TDP1LMNA
SCHEMBL8646118 0.82 THRA (0.66) ALDH1A1HPGDESR1THRATHRB
SCHEMBL1245355 0.80 KMT2A (0.55) KMT2AALDH1A1LMNARAB9ASMN1; SMN2
SCHEMBL8123048 0.80 SMN1; SMN2 (0.60) L3MBTL1ALDH1A1HPGDTHRATHRB
SCHEMBL21381324 0.79 TDP1 (0.57) KMT2AL3MBTL1ALDH1A1TDP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100197950-A1 PROCESS FOR PREPARING PHENOXY ACETIC ACID DERIVATIVES HIGH POINT PHARMACEUTICALS, LLC 2010-08-05 US disclosed
EP-2029507-A1 PROCESS FOR PREPARING PHENOXY ACETIC ACID DERIVATIVES High Point Pharmaceuticals, LLC (US) 2009-03-04 EP disclosed
WO-2007141295-A1 PROCESS FOR PREPARING PHENOXY ACETIC ACID DERIVATIVES HIGH POINT PHARMACEUTICALS, LLC (US) 2007-12-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100197950-A1 PROCESS FOR PREPARING PHENOXY ACETIC ACID DERIVATIVES HAAO, HPD, PAH KMT2A 395/4885L3MBTL1 4524/4885ALDH1A1 71/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.