Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9565915 | 0.83 | ALDH1A1 (0.59) | KMT2AMEN1CYP1A2CYP3A4HDAC1 | |
| SCHEMBL27469935 | 0.81 | RAB9A (0.59) | KMT2AHDAC1HDAC6ALDH1A1SMN1; SMN2 | |
| SCHEMBL25271022 | 0.81 | ALDH1A1 (0.57) | KMT2AMEN1CYP1A2CYP3A4HDAC1 | |
| SCHEMBL30384869 | 0.80 | RAB9A (0.58) | KMT2AMEN1HDAC1HDAC6THRB | |
| SCHEMBL20605956 | 0.78 | KMT2A (0.56) | KMT2AMEN1CYP1A2CYP3A4HDAC1 | |
| SCHEMBL1106964 | 0.78 | HDAC1 (0.62) | KMT2AMEN1CYP1A2CYP3A4HDAC1 | |
| SCHEMBL4731567 | 0.78 | ALDH1A1 (0.66) | KMT2AMEN1CYP1A2CYP3A4HDAC1 | |
| SCHEMBL3819701 | 0.77 | KMT2A (0.71) | KMT2AMEN1CYP1A2CYP3A4HDAC1 | |
| SCHEMBL4203340 | 0.77 | L3MBTL1 (0.61) | KMT2AMEN1CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL4263053 | 0.77 | HDAC1 (0.53) | KMT2AMEN1CYP1A2CYP3A4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116870016-B | Heteroaromatic compound and medical application thereof | 希格生科（深圳）有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-117412981-A | Phosphine oxide derivative and preparation method and application thereof | 希格生科（深圳）有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-116870016-A | Heteroaromatic compound and medical application thereof | 希格生科（深圳）有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-115785154-A | Heteroaromatic ring compounds and medical use thereof | 希格生科（深圳）有限公司 | 2023-03-14 | — | — | CN | disclosed |