Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL155113 | 0.85 | ALDH1A1 (0.61) | ALDH1A1TDP1CYP3A4TSHRHSD17B10 | |
| Bromide SCHEMBL7931348 | 0.83 | ALDH1A1 (0.59) | ALDH1A1TDP1CYP3A4TSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL28039298 | 0.83 | ALDH1A1 (0.61) | ALDH1A1TDP1CYP3A4TSHRHSD17B10 | |
| SCHEMBL2373683 | 0.72 | HRH4 (0.46) | ALDH1A1TDP1CYP3A4TSHRHSD17B10 | |
| SCHEMBL30988808 | 0.72 | SLC6A4 (0.39) | ALDH1A1TDP1L3MBTL1GAAMGAM | |
| SCHEMBL3856079 | 0.72 | ALDH1A1 (0.66) | ALDH1A1TDP1TSHRHSD17B10MAPT | |
| SCHEMBL1299012 | 0.72 | ALDH1A1 (0.52) | ALDH1A1TDP1CYP3A4TSHRHSD17B10 | |
| SCHEMBL30184555 | 0.71 | ALDH1A1 (0.40) | ALDH1A1TDP1CYP3A4TSHRHSD17B10 | |
| SCHEMBL31449970 | 0.69 | ALDH1A1 (0.44) | ALDH1A1TDP1CYP3A4TSHRHSD17B10 | |
| SCHEMBL25033177 | 0.69 | ALDH1A1 (0.43) | ALDH1A1TDP1CYP3A4TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4384510-A1 | COMPOUNDS TARGETING MUTANT OF P53 | Jacobio Pharmaceuticals Co., Ltd. (CN) | 2024-06-19 | — | — | EP | disclosed |
| WO-2023016434-A1 | COMPOUNDS TARGETING MUTANT OF P53 | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2023-02-16 | — | — | WO | disclosed |