Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 15/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30185522 | 0.89 | RORC (0.59) | RORC | |
| SCHEMBL30185525 | 0.88 | RORC (0.48) | RORC | |
| SCHEMBL30185508 | 0.78 | RORC (0.58) | RORC | |
| SCHEMBL28603444 | 0.77 | RORC (0.63) | RORC | |
| SCHEMBL30185535 | 0.77 | RORC (0.59) | RORCPPARG | |
| SCHEMBL19360602 | 0.77 | RORC (0.62) | RORC | |
| SCHEMBL30185519 | 0.76 | RORC (0.58) | RORC | |
| SCHEMBL28595332 | 0.75 | RORC (0.80) | RORC | |
| SCHEMBL30185505 | 0.74 | RORC (0.59) | RORCPPARG | |
| SCHEMBL30185523 | 0.74 | RORC (0.51) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112759541-B | Indole-like derivatives and uses thereof | 复旦大学 | 2023-03-17 | — | — | CN | disclosed |