Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 4/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 4/20 | 0.42 |
| ▸ | HTR2C | P28335 | 4/20 | 0.42 |
| ▸ | HTR2B | P41595 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.38 |
| ▸ | PARP11 | Q9NR21 | 2/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Boric Acid SCHEMBL29099586 | 0.94 | PARP3 (0.49) | PARP3PARP1PARP2HTR2AHTR2C | |
| SCHEMBL8931375 | 0.84 | PARP3 (0.49) | PARP3PARP1PARP2HTR2AHTR2C | |
| SCHEMBL31412980 | 0.77 | PARP10 (0.44) | PARP3PARP1HTR2AHTR2CHTR2B | |
| SCHEMBL26510292 | 0.77 | PARP10 (0.44) | PARP3PARP1HTR2AHTR2CHTR2B | |
| SCHEMBL26121467 | 0.77 | TDP2 (0.37) | PARP3PARP1PARP2PARP10PARP11 | |
| SCHEMBL25758208 | 0.76 | HTR2C (0.33) | PARP1PARP2HTR2CTNKS2 | |
| SCHEMBL29458430 | 0.74 | PARP3 (0.43) | PARP3PARP1PARP2HTR2AHTR2C | |
| SCHEMBL6635520 | 0.74 | PARP3 (0.53) | PARP3PARP1HTR2AHTR2CHTR2B | |
| SCHEMBL21187107 | 0.74 | PARP3 (0.53) | PARP3PARP1PARP2HTR2AHTR2C | |
| SCHEMBL12220005 | 0.74 | PARP3 (0.53) | PARP3PARP1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611883-B | PI3K alpha inhibitor with double-ring structure, and preparation method and application thereof | 生物岛实验室 | 2025-03-28 | — | — | CN | disclosed |
| CN-115611883-A | PI3K alpha inhibitor with bicyclic structure and preparation method and application thereof | 生物岛实验室 | 2023-01-17 | — | — | CN | disclosed |