Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 4/20 | 0.45 |
| ▸ | HTR2C | P28335 | 4/20 | 0.45 |
| ▸ | HTR2B | P41595 | 4/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.45 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.40 |
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 2/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12220005 | 1.00 | PARP3 (0.53) | PARP3HTR2AHTR2CHTR2BMKNK1 | |
| SCHEMBL8180143 | 0.79 | MKNK1 (0.44) | PARP3MKNK1CDC7CA12CA9 | |
| SCHEMBL8178575 | 0.79 | MKNK1 (0.44) | PARP3MKNK1CDC7CA12CA9 | |
| SCHEMBL21187107 | 0.77 | PARP3 (0.53) | PARP3HTR2AHTR2CHTR2BCA12 | |
| SCHEMBL11750196 | 0.77 | PARP3 (0.61) | PARP3HTR2AHTR2CHTR2BCA12 | |
| SCHEMBL21187216 | 0.77 | PARP3 (0.49) | PARP3HTR2AHTR2CHTR2BCA12 | |
| SCHEMBL21187169 | 0.77 | PARP3 (0.49) | PARP3HTR2AHTR2CHTR2BCA12 | |
| SCHEMBL13361350 | 0.77 | PARP10 (0.47) | HTR2AHTR2CHTR2BMKNK1CDC7 | |
| SCHEMBL12242052 | 0.77 | PARP10 (0.47) | HTR2AHTR2CHTR2BMKNK1CDC7 | |
| SCHEMBL8931375 | 0.77 | PARP3 (0.49) | PARP3HTR2AHTR2CHTR2BCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025089147-A1 | HERBICIDAL COMPOSITION | 株式会社エス・ディー・エス バイオテック | 2025-05-01 | — | — | WO | disclosed |
| WO-2023210623-A1 | HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME | 株式会社エス・ディー・エス バイオテック | 2023-11-02 | — | — | WO | disclosed |
| WO-2019141095-A1 | AMIDINE AND GUANIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-07-25 | — | — | WO | disclosed |
| US-10016410-B2 | Tetrahydroisoquinolin-1-one derivative or salt thereof | SELDAR PHARMA INC. (US) | 2018-07-10 | — | — | US | disclosed |
| US-20170189390-A1 | TETRAHYDROISOQUINOLIN-1-ONE DERIVATIVE OR SALT THEREOF | SELDAR PHARMA INC. (US) | 2017-07-06 | — | — | US | disclosed |
| US-20130267712-A1 | AROMATIC KETONE SYNTHESIS WITH AMIDE REAGENTS AND RELATED REACTIONS | BOARD OF TRUSTEES OF NORTHERN ILLINOIS UNIVERSITY (US) | 2013-10-10 | — | — | US | disclosed |
| US-20130267712-A1 | AROMATIC KETONE SYNTHESIS WITH AMIDE REAGENTS AND RELATED REACTIONS | BOARD OF TRUSTEES OF NORTHERN ILLINOIS UNIVERSITY (US) | 2013-10-10 | — | — | US | disclosed |
| EP-1144409-B1 | PHENYL UREA AND PHENYL THIOUREA DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2004-11-17 | — | — | EP | disclosed |
| US-6596730-B1 | Phenyl urea and phenyl thiourea derivatives | SMITHKLINE BEECHAM P.L.C. (GB) | 2003-07-22 | — | — | US | disclosed |
| EP-1144409-A2 | PHENYL UREA AND PHENYL THIOUREA DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000047580-A2 | PHENYL UREA AND PHENYL THIOUREA DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2000-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170189390-A1 | TETRAHYDROISOQUINOLIN-1-ONE DERIVATIVE OR SALT THEREOF | BRS3, BDKRB2, NTSR2 | PARP3 3125/4885HTR2A 93/4885HTR2C 163/4885 |
| US-10016410-B2 | Tetrahydroisoquinolin-1-one derivative or salt thereof | BRS3, BDKRB2, NTSR2 | PARP3 3125/4885HTR2A 93/4885HTR2C 163/4885 |
| US-20130267712-A1 | AROMATIC KETONE SYNTHESIS WITH AMIDE REAGENTS AND RELATED REACTIONS | NAAA, AADAC, NISCH | PARP3 4520/4885HTR2A 2476/4885HTR2C 2399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.