Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC3 | Q13507 | 10/20 | 1.00 |
| ▸ | TRPC6 | Q9Y210 | 10/20 | 1.00 |
| ▸ | TRPA1 | O75762 | 2/20 | 1.00 |
| ▸ | CACNA1C | Q13936 | 2/20 | 1.00 |
| ▸ | SCN5A | Q14524 | 2/20 | 1.00 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 1.00 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 1.00 |
| ▸ | HCRTR1 | O43613 | 10/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26459111 | 1.00 | TRPC3 (1.00) | TRPC3TRPC6TRPA1CACNA1CSCN5A | |
| SCHEMBL798463 | 1.00 | TRPC3 (1.00) | TRPC3TRPC6TRPA1CACNA1CSCN5A | |
| SCHEMBL26458205 | 0.91 | TRPC3 (0.83) | TRPC3TRPC6TRPA1CACNA1CSCN5A | |
| SCHEMBL26458213 | 0.91 | TRPC3 (0.83) | TRPC3TRPC6TRPA1CACNA1CSCN5A | |
| SCHEMBL789038 | 0.87 | TRPC3 (0.77) | TRPC3TRPC6TRPA1CACNA1CSCN5A | |
| SCHEMBL790188 | 0.84 | TRPC3 (0.72) | TRPC3TRPC6TRPA1CACNA1CSCN5A | |
| SCHEMBL806600 | 0.84 | TRPC3 (1.00) | TRPC3TRPC6TRPA1CACNA1CSCN5A | |
| SCHEMBL26459144 | 0.84 | TRPC3 (0.72) | TRPC3TRPC6TRPA1CACNA1CSCN5A | |
| SCHEMBL790044 | 0.83 | TRPC3 (0.71) | TRPC3TRPC6TRPA1CACNA1CSCN5A | |
| SCHEMBL806708 | 0.81 | TRPC3 (0.68) | TRPC3TRPC6TRPA1CACNA1CSCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4103245-B1 | ADMINISTRATION OF CALCIUM CHANNEL TRPC6 INHIBITORS USING BALLOONS, STENTS OR OTHER MEDICAL DEVICES | KLINIKUM DER TECHNISCHEN UNIV MUENCHEN TUM KLINIKUM (DE) | 2026-04-01 | — | — | EP | disclosed |
| CN-112204017-B | Benzisoxazole compounds | 国立大学法人大阪大学 | 2024-08-20 | — | — | CN | disclosed |
| US-11976062-B2 | Benzisoxazole compound | OSAKA UNIVERSITY (JP) | 2024-05-07 | — | — | US | disclosed |
| EP-3789383-B9 | INHIBITORS OF THE TRPC3 OR TRPC6 CHANNEL | UNIV OSAKA (JP) | 2024-02-28 | — | — | EP | disclosed |
| EP-3789383-B1 | INHIBITORS OF THE TRPC3 OR TRPC6 CHANNEL | UNIV OSAKA (JP) | 2023-11-29 | — | — | EP | disclosed |
| US-20230137816-A1 | ADMINISTRATION OF CALCIUM CHANNEL TRPC6 INHIBITORS USING BALLOONS, STENTS OR OTHER MEDICAL DEVICES | DEUTSCHES HERZZENTRUM MUENCHEN DES FREISTAATES BAYERN (DE) | 2023-05-04 | — | — | US | disclosed |
| US-20230114195-A1 | BENZISOXAZOLE COMPOUND | KYOTO UNIVERSITY (JP) | 2023-04-13 | — | — | US | disclosed |
| US-11548882-B2 | Benzisoxazole compound | OSAKA UNIVERSITY (JP) | 2023-01-10 | — | — | US | disclosed |
| EP-4103245-A1 | ADMINISTRATION OF CALCIUM CHANNEL TRPC6 INHIBITORS USING BALLOONS, STENTS OR OTHER MEDICAL DEVICES | Klinikum rechts der Isar der Technischen Universität München (DE) | 2022-12-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230137816-A1 | ADMINISTRATION OF CALCIUM CHANNEL TRPC6 INHIBITORS USING BALLOONS, STENTS OR OTHER MEDICAL DEVICES | TRPC6, TRPC1, ORAI1 | TRPC3 6/4885TRPC6 1/4885TRPA1 26/4885 |
| US-11976062-B2 | Benzisoxazole compound | CBR1, CYP2S1, CYP2E1 | TRPC3 2975/4885TRPC6 3601/4885TRPA1 1638/4885 |
| US-11548882-B2 | Benzisoxazole compound | CBR1, CYP2S1, CYP2E1 | TRPC3 3014/4885TRPC6 3644/4885TRPA1 1697/4885 |
| US-20230114195-A1 | BENZISOXAZOLE COMPOUND | CBR1, CYP2S1, CYP2E1 | TRPC3 2830/4885TRPC6 3541/4885TRPA1 1702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.