Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.53 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.47 |
| ▸ | MTOR | P42345 | 2/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.47 |
| ▸ | ATR | Q13535 | 2/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PRKCG | P05129 | 1/20 | 0.46 |
| ▸ | PRKCB | P05771 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKCH | P24723 | 1/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28923309 | 0.85 | GPR119 (0.52) | GPR119NR3C1PIK3CAMTORPIK3CG | |
| SCHEMBL29129979 | 0.80 | GPR119 (0.53) | GPR119NR3C1PIK3CAMTORPIK3CG | |
| SCHEMBL30059506 | 0.80 | GPR119 (0.53) | GPR119NR3C1PIK3CAMTORPIK3CG | |
| SCHEMBL30186809 | 0.79 | USP30 (0.51) | GPR119NR3C1PIK3CAMTORPIK3CG | |
| SCHEMBL25356444 | 0.78 | NR3C1 (0.53) | GPR119NR3C1PIK3CAMTORPIK3CG | |
| SCHEMBL23914934 | 0.77 | LMNA (0.51) | GPR119NR3C1CYP3A4KDM4EPKM | |
| SCHEMBL23531650 | 0.77 | GPR119 (0.55) | GPR119KDM4EPKMPOLBMAPT | |
| SCHEMBL12459062 | 0.77 | GPR119 (0.60) | GPR119NR3C1PIK3CAMTORPIK3CG | |
| SCHEMBL23531618 | 0.77 | EGFR (0.51) | GPR119PIK3CAPIK3CGKDM4EPKM | |
| SCHEMBL21060691 | 0.77 | GPR119 (0.68) | GPR119NR3C1PIK3CAMTORPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013010453-A1 | CHEMOKING RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2013-01-24 | — | — | WO | disclosed |