Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 1/20 | 0.46 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | RBP4 | P02753 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 2/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19740830 | 1.00 | SLC5A1 (0.46) | SLC5A1SLC5A2NAMPTRBP4ALOX5AP | |
| SCHEMBL28862478 | 0.86 | ALOX5AP (0.48) | SLC5A1SLC5A2NAMPTALOX5APFEN1 | |
| SCHEMBL23693081 | 0.84 | GPR119 (0.48) | SLC5A1SLC5A2NAMPTALOX5APFEN1 | |
| SCHEMBL26928473 | 0.83 | SLC5A1 (0.46) | SLC5A1SLC5A2NAMPTRBP4ALOX5AP | |
| SCHEMBL796329 | 0.79 | NAMPT (0.54) | SLC5A1SLC5A2NAMPTALOX5APFEN1 | |
| SCHEMBL30324594 | 0.79 | USP30 (0.43) | POLBSTSGPR119ANO1 | |
| SCHEMBL20757641 | 0.78 | PDE4B (0.46) | POLBGPR119ANO1 | |
| SCHEMBL30094557 | 0.78 | PDE4B (0.46) | POLBGPR119ANO1 | |
| SCHEMBL28398406 | 0.78 | STS (0.48) | POLBSTSGPR119FAAH | |
| SCHEMBL21618375 | 0.78 | GPR119 (0.48) | SLC5A1SLC5A2NAMPTALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109310668-B | Positive allosteric modulators of muscarinic acetylcholine receptor M4 | 范德比尔特大学 | 2023-01-24 | — | — | CN | disclosed |