Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 8/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL190497 | 0.82 | GPR119 (0.53) | GPR119POLB | |
| SCHEMBL29495616 | 0.82 | GPR119 (0.53) | GPR119POLB | |
| SCHEMBL17645463 | 0.81 | NPC1 (0.41) | NPC1RAB9A | |
| SCHEMBL13390150 | 0.81 | STS (0.58) | STSPTPN2PTPN1PTPN6GPR119 | |
| SCHEMBL28401978 | 0.81 | ALDH1A1 (0.46) | NPC1USP30POLB | |
| SCHEMBL17645361 | 0.79 | TAS1R3 (0.39) | NPC1RAB9A | |
| SCHEMBL30187837 | 0.78 | SLC5A1 (0.46) | STSGPR119POLBFAAH | |
| SCHEMBL19740830 | 0.78 | SLC5A1 (0.46) | STSGPR119POLBFAAH | |
| SCHEMBL14239639 | 0.78 | GPR119 (0.50) | STSGPR119POLB | |
| SCHEMBL14239932 | 0.77 | FAAH (0.50) | STSGPR119POLBFAAHFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111196804-B | TGF-beta R1 inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-111196804-A | TGF- β R1 inhibitor and application thereof | 南京圣和药业股份有限公司 | 2020-05-26 | — | — | CN | disclosed |