Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL30188640

O=C(COc1ccc2c(c1)CCN2)OCc1ccccc1.O=C(O)C(F)(F)F

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAOA P21397 7/20 0.50
MAOB P27338 7/20 0.50
KDM4E B2RXH2 1/20 0.46
LMNA P02545 1/20 0.46
POLB P06746 1/20 0.46
HRH3 Q9Y5N1 1/20 0.40
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39
RXRG P48443 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23810763 0.94 MAOA (0.56) MAOAMAOBKDM4ELMNAPOLB
Trifluoroacetic Acid SCHEMBL23320781 0.83 ALOX15 (0.51) MAOAMAOBKDM4EHRH3RXRA
SCHEMBL3875255 0.80 MAOA (0.68) MAOAMAOBHRH3
Hydrochloric Acid SCHEMBL3902331 0.79 MAOA (0.66) MAOAMAOBHRH3
SCHEMBL23320783 0.79 HRH3 (0.44) MAOAMAOBKDM4EHRH3RXRA
SCHEMBL6489929 0.75 HRH3 (0.48) MAOAMAOBKDM4ELMNAHRH3
Hydrochloric Acid SCHEMBL3902342 0.74 MAOB (0.59) MAOAMAOBHRH3
Trifluoroacetic Acid SCHEMBL3902745 0.74 S1PR1 (0.54) MAOAMAOBHRH3
SCHEMBL13598169 0.73 MAOB (0.58) MAOAMAOBKDM4EHRH3
SCHEMBL6421129 0.73 MAOA (0.64) MAOAMAOBHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11542273-B2 Amide compound having bet proteolysis-inducing action and medicinal application thereof MITSUBISHI TANABE PHARMA CORPORATION (JP) 2023-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11542273-B2 Amide compound having bet proteolysis-inducing action and medicinal application thereof BET1, BRD4, PHKB MAOA 4398/4885MAOB 4471/4885KDM4E 261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.