Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.32 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29301526 | 0.82 | TP53 (0.37) | RIOK2 | |
| SCHEMBL31613977 | 0.81 | KDM4C (0.39) | SMARCA2 | |
| SCHEMBL27972604 | 0.81 | KDM4E (0.38) | — | |
| SCHEMBL30189285 | 0.81 | P2RX7 (0.33) | — | |
| SCHEMBL22615150 | 0.81 | KDM4C (0.39) | SMARCA2 | |
| SCHEMBL27972528 | 0.77 | EGFR (0.42) | RIOK2 | |
| SCHEMBL24586223 | 0.76 | CYP3A4 (0.41) | — | |
| SCHEMBL14915338 | 0.76 | CYP3A4 (0.41) | — | |
| SCHEMBL29925482 | 0.76 | CYP3A4 (0.41) | — | |
| SCHEMBL22615180 | 0.70 | APLNR (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4149945-A1 | SUBSTITUTED TRICYCLIC AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME | Arbutus Biopharma Corporation (CA) | 2023-03-22 | — | — | EP | disclosed |